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Crataegus monogyna
CautionEingriffeliger Weißdorn · (Crataegus monogyna)
Rose family (Rosaceae)
Description
A thorny hedgerow shrub, hawthorn has lined European field margins and woodland edges for centuries — foaming white blossom in May, glossy red haws by autumn. It is the leaves and flowers, gathered in May, that are used, rich in oligomeric procyanidins and flavonoids such as hyperoside and rutin. Standardised extracts from these parts have a well-established monograph supporting heart and circulatory function, though the effect only builds after four to six weeks of regular use and is therefore unsuited to acute complaints. Cardiac symptoms such as palpitations, chest pressure or breathlessness should always be medically assessed first, before hawthorn is considered as a supportive measure. Without medical supervision, use is generally limited to six weeks.
Standardised dry extract (well-established use) for supportive treatment of mild heart failure NYHA II — leading preparation WS 1442.
Preparation & dosage
STANDARDISED DRY EXTRACT (EMA well-established use): Standardised dry extracts of hawthorn leaf with flower (e.g. WS 1442, LI 132), DER 4–7:1, ethanol 45 % m/m or methanol 70 % V/V, standardised to 18.75 % oligomeric procyanidins. Daily dose 160–900 mg, split into 2–3 single doses with meals. Indication: supportive treatment of declining cardiac performance corresponding to NYHA stage II (mild exertional dyspnoea, chest pressure, fatigue). Effect onset after 4–6 weeks — no acute action. Do not self-medicate confirmed heart failure; hawthorn is adjunctive. Worsening symptoms, oedema, dyspnoea at rest or chest pain require immediate medical attention.
- Liquid amount
- 5–10 ml
- Doses per day
- 3×
- Max duration
- 6 weeks
⚠ Age restriction: ≥ 18 years — Per EMA, adults only — insufficient data for children/adolescents under 18.
Traditional infusion of leaf with flower for nervous mild cardiac complaints (NYHA II supportive) after medical evaluation.
Preparation & dosage
INFUSION: 1–1.5 g of finely cut hawthorn leaf with flower in 150–250 ml boiling water, covered, steep 10–15 min, strain. 2–3× daily fresh, between meals. Daily dose ~3–4.5 g. Traditional use (EMA traditional) for mild nervous cardiac complaints (palpitations, chest pressure) after exclusion of serious causes. Slow acting — patience for 2–4 weeks. Beyond 6 weeks without improvement, consult doctor.
- Dry amount
- 1–1.5 g
- Doses per day
- 3×
- Max duration
- 6 weeks
⚠ Age restriction: ≥ 18 years — Per EMA, adults only.
Traditional tincture for mild nervous cardiac complaints — alternative to tea when ethanol is acceptable.
Preparation & dosage
TINCTURE (DER 1:5 in 45–70 % ethanol): 1–2 ml (~20–40 drops) 3× daily, diluted in water, before or between meals. Effect after 2–4 weeks of continuous use. If complaints persist beyond 6 weeks, consult a doctor. Traditional use for mild nervous cardiac complaints (palpitations, restlessness), not for acute treatment.
- Liquid amount
- 1–2 ml
- Doses per day
- 3×
- Max duration
- 6 weeks
⚠ Age restriction: ≥ 18 years — Adults only. Due to ethanol content not for alcohol dependence, liver disease, or epilepsy.
Folk calming and sleep tea from hawthorn flowers — mild nervine, often blended with lemon balm or valerian.
Preparation & dosage
FOLK EVENING TEA: 1–2 tsp dried hawthorn flowers (optionally with lemon balm or valerian) in 250 ml hot water, covered, steep 8–10 min, strain. 1 cup late afternoon and 1 cup ~30 min before bedtime. Folk use for mild calming with restlessness and nervous trouble falling asleep. NOT a pharmacological sedative — mild adjunct. For chronic sleep problems, seek medical evaluation.
- Dry amount
- 1–2 g
- Doses per day
- 2×
- Max duration
- 4 weeks
Folk berry decoction for menopausal complaints, mild restlessness and sleep issues — WHO lists Fructus Crataegi as a traditional cardiovascular remedy.
Preparation & dosage
BERRY TEA: 2–3 tsp dried, lightly crushed hawthorn berries in 250 ml cold water, bring to boil, simmer 10–15 min (decoction), strain. 1–2 cups daily. Folk use for menopausal complaints (hot flushes, restlessness, climacteric palpitations) and mild sleep support. Milder action than leaf-flower preparation — berries differ in compound profile (more procyanidins, fewer flavonoids). Adjunctive use only.
- Dry amount
- 2–3 g
- Doses per day
- 2×
- Max duration
- 6 weeks
Edible berry — jam, jelly, liqueur, flour substitute; traditional famine food and sweet-tart wild fruit.
Preparation & dosage
KITCHEN: Fully ripe deep-red hawthorn berries (Sept–Oct, sweetest after first frost) are edible — mealy, mildly sweet-tart. Uses: cooked into jam, jelly or fruit butter (remove stones or press through sieve — the hard stone is inedible), added to apple sauce, infused as hawthorn liqueur (with sugar and spirit, 6–8 weeks), dried and ground as flour substitute (up to ~25 %). Traditional farm/famine food, roasted as coffee substitute in hard times.
IMPORTANT: Hawthorn treats SYMPTOMS — diagnosis required first. Cardiac symptoms (palpitations, pressure, dyspnoea, exercise intolerance, leg oedema) always need medical evaluation. Self-treatment of manifest heart failure without diagnosis is dangerous. Onset of action only after 4–6 weeks — not for acute use. Sudden dyspnoea, persisting chest pain, radiation to arm/jaw, cold sweat or sudden leg swelling → emergency immediately. EMA limits self-medication to 6 weeks without medical supervision. ASPCA classification (accessed 2026-08-10): non-toxic to cats. The ASPCA classifies the whole genus this way.
⏱ Max continuous use: 6 weeks
Per EMA not recommended in pregnancy due to lack of data. Avoid therapeutic doses (tea, tincture, dry extract). Culinary use of ripe berries (jam, jelly, occasional liqueur) is considered safe.
Per EMA not recommended during lactation due to lack of data. Culinary berry use is unproblematic.
Standardised dry extracts and tincture not for children/adolescents under 12 (EMA — no safety data). Berry preserves, jam, mild tea in household amounts are safe. Cardiac complaints in children require medical assessment, not self-treatment.
Drug interactions
Herzglykoside (Digitalis, Digoxin, Digitoxin)
Hawthorn extracts inhibit cAMP phosphodiesterase and sensitise to calcium → positive inotropic effect, additive with cardiac glycosides. Theoretical risk of glycoside overdose (bradycardia, AV block, arrhythmia). Combination only under strict medical supervision with plasma level monitoring.
Antihypertensiva (Nitrate, ACE-Hemmer, Betablocker, Calciumantagonisten)
Hawthorn is vasodilating (NO-mediated) and mildly hypotensive. Additive effect with antihypertensives — risk of hypotension, dizziness, syncope. Monitor blood pressure, adjust dose if needed.
Antiarrhythmika (Amiodaron, Sotalol, Klasse-I-Antiarrhythmika)
Hawthorn has weak antiarrhythmic activity (prolongation of refractory period). Theoretical additive effect with antiarrhythmics — risk of proarrhythmia or QT prolongation. Clinical data limited; combine only under ECG monitoring.
MAO-Hemmer (Moclobemid, Tranylcypromin, Selegilin)
Hawthorn flowers contain trace biogenic amines (phenylethylamine, tyramine). With non-selective MAO inhibitors theoretical risk of hypertensive crisis due to reduced tyramine breakdown. Clinically rare at normal doses; monitor blood pressure.
Contraindications
- Hypersensitivity to hawthorn or other Rosaceae.
- Children/adolescents under 12 (standard preparations) or under 18 (EMA well-established NYHA II indication) — insufficient data.
- Acute heart failure, unstable angina, acute MI, severe arrhythmias, pulmonary oedema — emergency care, no hawthorn.
- Pregnancy and lactation (therapeutic doses) — avoid due to lack of data.
Harvested part: flowers and leaves (May), berries (autumn)
- Time of day:
- On a dry, sunny morning (10–12), once dew has fully evaporated — constituents (OPCs, flavonoids) are then most concentrated.
- Drying:
- Pick fully opened flowering corymbs with attached young leaves (1–2 leaves below the cluster), cut off thick woody parts. Beware of sharp thorns — wear sturdy gloves and long sleeves. Dry in a single layer on cloth or screens in shade, well-ventilated, max 35–40 °C, turn occasionally. Harvest window is very narrow — full bloom often lasts only 7–10 days, then flowers turn brown and quickly lose potency.
- Storage:
- 12 months — Airtight in dark jars or tins, dry, cool. Use within 1 year — potency drops sharply after. Discard if browning or musty smell.
- Time of day:
- Dry mornings or midday in late summer / early autumn — pick berries when deep red and fully ripe, ideally after the first light frost (milder, sweeter, better procyanidin availability).
- Drying:
- Remove stems, wash, halve or leave whole (whole berries take longer). Dehydrator at 40–50 °C or oven with door slightly ajar ~50 °C for 12–24 h until leathery-hard. Air-drying only in very dry warm weather (otherwise mould risk).
- Storage:
- 12 months — Airtight, dark, cool, dry. Use within 1 year. Fresh berries are best processed directly into puree, liqueur or tincture — fresh processing preserves more procyanidins.
- Oligomere Procyanidine (OPC, B-Reihe: Procyanidin B2, B5, C1)OtherContent: 1–3 %Aerial parts
Lead compound group of standardised extracts (WS 1442 standardised to 18.75 % OPCs). Catechin/epicatechin oligomers — positive inotropic (PDE inhibition, calcium sensitisation), vasodilating (endothelial NO release), antioxidant, capillary-protective.
- Flavonoide (Hyperosid, Rutin, Vitexin, Vitexin-2-O-rhamnosid, Quercetin)FlavonoidContent: 1–2 %Flower
Quantitative lead compounds of the flowers (hyperoside dominates in leaves, vitexin-rhamnoside in flowers). Improve coronary perfusion, mildly antioxidant and endothelium-protective. EMA standardisation on flavonoid content.
- Triterpensäuren (Crataegolsäure, Ursolsäure, Oleanolsäure)OtherContent: 0,5–1,4 %Aerial parts
Pentacyclic triterpenes with mild positive inotropic, antiarrhythmic and anti-inflammatory properties. Contribute to the cardioprotective whole-extract effect.
- Phenolcarbonsäuren (Chlorogensäure, Kaffeesäure)Phenolic acidContent: 0,3–0,5 %Aerial parts
Mildly antioxidant and vasoprotective; complement the antioxidant effect of procyanidins and flavonoids.
- Biogene Amine (Phenylethylamin, Tyramin, Methylamin — Spuren)OtherContent: SpurenFlower
Trace amounts only; pharmacologically irrelevant at normal doses but theoretically relevant when combined with non-selective MAO inhibitors (tyramine handling).
- Catechine und Epicatechin (monomere Gerbstoffe)TanninContent: 1–2 %Aerial parts
Monomeric precursors of the procyanidins. Antioxidant and mildly astringent; contribute to vascular wall stabilisation.
- Procyanidine der B-Reihe (Procyanidin B2 dominant)OtherContent: 0,5–1 %Fruit
Dominant procyanidin fraction in the berries — fruits show higher OPC and lower flavonoid content than flowers/leaves. Explains different activity profile of berry vs. flower-leaf preparations.
- Ätherisches Öl (in Blüten — Spuren)Essential oilContent: SpurenFlower
Very small amounts of volatile constituents (incl. trimethylamine) responsible for the characteristic slightly fishy-sweet flower scent. Pharmacologically irrelevant.
- [1]MonographEMA/HMPC/159075/2014 — European Union herbal monograph on Crataegus monogyna Jacq., C. laevigata (Poir.) DC. and hybrids, folium cum flore (Final)(accessed: 2026-05-18)
- [2]MonographKommission E — Crataegi folium cum flore (Weißdornblätter mit Blüten), Monographie (positiv), BAnz Nr. 133, 1994(accessed: 2026-05-19)
- [3]MonographESCOP Monographs — Crataegi folium cum flore (Hawthorn Leaf and Flower), 2nd edition (incl. supplement)(accessed: 2026-05-19)
- [4]MonographWHO Monographs on Selected Medicinal Plants — Volume 2: Fructus Crataegi(accessed: 2026-05-19)
- [6]MonographPlants For A Future (PFAF) — Crataegus monogyna database entry(accessed: 2026-05-19)
- [7]MonographHeilkräuter-Lexikon — Weißdorn (Crataegus monogyna / laevigata)(accessed: 2026-05-19)
- [9]MonographASPCA Animal Poison Control — Haws (Crataegus species)(accessed: 2026-08-10)
- [5]BookMadaus, Gerhard — Lehrbuch der biologischen Heilmittel, Band II: Crataegus (Weißdorn), 1938 (Public Domain)(accessed: 2026-05-19)
- [8]WikipediaEingriffeliger Weißdorn (Wikipedia DE)(accessed: 2026-05-19)