© Walther Otto Müller · Public domain · Commons
Salvia officinalis
CautionEchter Salbei · (Salvia officinalis)
Mint family (Lamiaceae)
Description
Grey-green, slightly wrinkled, velvety leaves distinguish this Mediterranean subshrub of the mint family (Lamiaceae) from other culinary herbs. Harvested before flowering, the leaves contain essential oil with thujone, 1,8-cineole and camphor, along with rosmarinic acid, salvianolic acids and the diterpenes carnosol and carnosolic acid. The EMA classifies gargles for inflammation of the mouth and throat, as well as tea for mild digestive complaints and excessive sweating, as 'well-established use'. In folk practice, an infusion is also applied externally to minor wounds. IMPORTANT: because of its uterine-contracting thujone content, therapeutic sage preparations are contraindicated in pregnancy, and during breastfeeding sage may suppress milk production. Continuous use should, per the monograph, not exceed six weeks, and pure sage essential oil must never be taken internally.
CONTRAINDICATED during pregnancy
Culinary amounts as a spice are safe. Avoid therapeutic doses (tea, tincture, essential oil) throughout pregnancy — thujone content is uterine-contracting and potentially fetotoxic; classically used as an emmenagogue.
Critical drug interactions with:
Antikonvulsiva / Antiepileptika
Main indication per EMA HMPC and German Commission E: gargling and mouth-rinsing with sage leaf infusion for inflammations of the mouth and throat mucosa (stomatitis, gingivitis, pharyngitis, aphthae). Tannins act astringent, the essential oil antimicrobial and mildly local-anaesthetic.
Preparation & dosage
Pour 150 ml boiling water over 1-3 g finely cut sage leaves, cover and infuse for 10 minutes, strain and cool to body temperature. Gargle and rinse mouth several times a day (3-4 times); do not swallow when used intensively over several days.
- Dry amount
- 1–3 g
- Doses per day
- 4×
- Max duration
- 2 weeks
EMA HMPC and Commission E: sage tea as traditional use for mild dyspeptic complaints such as bloating, heartburn and flatulence. Essential oils and bitter principles act carminative, spasmolytic and choleretic.
Preparation & dosage
Pour 150 ml boiling water over 1-3 g finely cut sage leaves, cover and infuse for 10 minutes, then strain. Drink one cup 2-3 times daily between meals. Use continuously for a maximum of 4-6 weeks — avoid thujone accumulation.
- Dry amount
- 1–3 g
- Doses per day
- 3×
- Max duration
- 4 weeks
EMA HMPC: well-established traditional use as antihidrotic for excessive perspiration, particularly hyperhidrosis and menopausal symptoms (hot flushes, night sweats). Onset of action usually 1-2 hours, duration several hours.
Preparation & dosage
Pour 150 ml boiling water over 1-3 g dried sage leaves, infuse for 10 minutes, drink cold (cold preparation suppresses sweating more strongly than hot tea). One cup in the evening before bed for night sweats; for hyperhidrosis twice daily.
- Dry amount
- 1–3 g
- Doses per day
- 2×
- Max duration
- 6 weeks
Traditional ethanolic tincture for dyspeptic complaints and excessive sweating. More concentrated than tea, easy to transport — caution due to thujone content (ethanolic extracts contain more thujone than aqueous ones).
Preparation & dosage
1:5 tincture in 70 % ethanol from dried sage leaves. Usual daily dose: 1-3 ml (about 20-60 drops) in a little water, 2-3 times daily before meals. Do not use continuously for more than 4 weeks.
- Liquid amount
- 1–3 ml
- Doses per day
- 3×
- Max duration
- 4 weeks
Traditional folk-medicinal use as astringent and antimicrobial compress for poorly healing wounds, mild skin inflammations, insect bites and weeping eczema. Tannins act astringent, the essential oil bactericidal.
Preparation & dosage
Pour 250 ml boiling water over 3-5 g dried sage leaves, infuse for 15 minutes, strain. Soak a clean cloth in the warm infusion, wring lightly and apply to the affected skin area for 15-20 minutes. Once or twice daily.
- Dry amount
- 3–5 g
- Doses per day
- 2×
Traditional use as steam inhalation for the common cold, bronchitis and catarrhs of the upper respiratory tract. The essential oil with cineole and camphor is mucous-membrane active, expectorant and antimicrobial.
Preparation & dosage
Add 1-2 teaspoons dried sage leaves (or 2-3 drops sage oil) to a bowl with 500 ml hot (not boiling) water, cover head with a towel, close eyes and inhale steam for 5-10 minutes. Do not use in asthma, pertussis or children under 4 years.
- Dry amount
- 1–2 g
- Doses per day
- 2×
⚠ Age restriction: ≥ 4 years — Sage inhalation must not be used in children under 4 years due to thujone, cineole and camphor content — risk of laryngospasm with application near the face.
Classical Mediterranean culinary herb for fatty foods, poultry, pork, saltimbocca and bean dishes. Essential oils stimulate appetite and digestion and reduce belching after fatty meals. Culinary amounts pose no thujone concern.
Preparation & dosage
Therapeutic sage preparations (tea, tincture, essential oil) are contraindicated in pregnancy — thujone is uterine-contracting and potentially fetotoxic. During breastfeeding sage may suppress milk production (antigalactagogue — used deliberately for weaning). Maximum continuous use 4-6 weeks due to thujone accumulation (convulsive, hepatotoxic). Pure sage essential oil must never be taken internally — toxicity. Avoid in epilepsy. ASPCA classification (accessed 2026-08-10): non-toxic to dogs and cats.
⏱ Max continuous use: 6 weeks
Culinary amounts as a spice are safe. Avoid therapeutic doses (tea, tincture, essential oil) throughout pregnancy — thujone content is uterine-contracting and potentially fetotoxic; classically used as an emmenagogue.
Sage suppresses milk production (antigalactagogue) — used deliberately for weaning, therefore avoid during ongoing breastfeeding. Culinary amounts are safe. Use sage tea for intended weaning under guidance.
Sage essential oil must not be applied near the face in children under 4 years (risk of laryngospasm) and never internally due to thujone, cineole and camphor content. Mouth rinses with diluted tea from school age under supervision (do not swallow). Sage as culinary spice is safe.
Drug interactions
Antikonvulsiva / Antiepileptika
Thujone acts as non-competitive GABA-A receptor antagonist and may lower the seizure threshold. In epilepsy and concomitant antiepileptic therapy, high-dose or long-term sage preparations as well as sage essential oil should be avoided.
GABAerge Sedativa / Benzodiazepine / Alkohol
Thujone interacts with GABA-A receptors and may modulate the effect of GABAergic sedatives and the central nervous action of alcohol. Avoid concomitant use of therapeutic sage doses with alcohol or benzodiazepines.
Antidiabetika
Sage extracts may slightly lower fasting blood glucose (clinical data in type 2 diabetes available). Monitor blood-glucose values closely when taken alongside antidiabetic medication — risk of hypoglycaemia.
Antihypertensiva
Sage preparations may slightly affect blood pressure; monitor blood pressure during concomitant antihypertensive therapy, particularly with long-term higher doses.
Contraindications
- Known hypersensitivity to sage or other Lamiaceae.
- Pregnancy (therapeutic doses) — thujone is uterine-contracting and potentially fetotoxic.
- Epilepsy and other seizure disorders — thujone may lower the seizure threshold.
- Internal use of undiluted sage essential oil — risk of severe poisoning (convulsions, liver damage).
- Active breastfeeding when continued lactation is desired — sage suppresses milk production.
Harvested part: leaves (before flowering)
- Time of day:
- Late morning in dry, sunny weather once the dew has evaporated — essential-oil content is then highest. Peak oil content just before and during flowering (June/July).
- Drying:
- Dry sprigs in small, loose bundles upside down in a warm, airy, shaded place (max 35 °C, not in sun — aroma loss). Strip leaves from stems after 1-2 weeks.
- Storage:
- 12 months — Store in dark, tightly closed glass or tin containers, cool and dry. Whole leaves keep longer than cut material — essential oil evaporates with light, air and humidity.
- Time of day:
- During flowering (May to July) on sunny mornings late in the morning — cut flowers and young leafy shoots together. Flowering herb is mainly used for tinctures and inhalations.
- Drying:
- Lay flowering sprigs loosely or hang in loose bundles, dry shaded and airy at max 35 °C. Caution: flowers break apart more easily than leaves.
- Storage:
- 9 months — Store separately from pure leaf batches — flowering material is less aromatic and should be used within 9 months.
- Ätherisches Öl (alpha-Thujon, beta-Thujon, 1,8-Cineol, Campher, Borneol, alpha-Pinen)Essential oilContent: 1.0-2.8 %Leaf
Main active principle with high thujone content (alpha + beta thujone combined 35-60 %) — responsible for the antihidrotic and spasmolytic action but also for toxicity in overdose (convulsive, hepatotoxic). Thujone limits restrict continuous use to maximum 4-6 weeks.
- RosmarinsäurePhenolic acidContent: 2-3 %Leaf
Leading marker substance of Lamiaceae; strongly antioxidant, anti-inflammatory and antiviral. Water-soluble, therefore well extracted in aqueous infusion.
- Salvianolsäuren (Salvianolsäure A-K)Phenolic acidContent: 0.5-2 %Leaf
Complex family of phenolic acids built on the rosmarinic acid backbone; antioxidant, neuroprotective and anti-inflammatory. Increasingly investigated pharmacologically.
- Carnosol und CarnosolsäureOtherContent: 1-4 %Leaf
Phenolic diterpenes with marked antioxidant and anti-inflammatory effect; shared as marker substances with rosemary. Contribute to the preservative effect of sage food extracts.
- Flavonoide (Apigenin, Luteolin, Cirsiliol, 6-Methoxyluteolin)FlavonoidContent: 1-3 %Leaf
Methylated and glycosylated flavones with antioxidant, mildly spasmolytic and anti-inflammatory properties. Cirsiliol is a characteristic sage component.
- Gerbstoffe (Salviatannin, Lamiaceen-Gerbstoffe)TanninContent: 3-8 %Leaf
Astringent tannins of the Lamiaceae group — basis of the local anti-inflammatory action in mouth rinses and skin compresses. Tighten mucous membranes and reduce secretion.
- Triterpensäuren (Ursolsäure, Oleanolsäure)OtherContent: 1-4 %Leaf
Pentacyclic triterpenes with anti-inflammatory, hepatoprotective and mildly antimicrobial effect; contribute to the action of external preparations (compresses, mouth rinses).
- Bitterstoffe (diterpenoide Bitterstoffe, Picrosalvin)BitterContent: Spurenanteile bis 0.5 %Leaf
Bitter diterpenes contribute to appetite- and bile-flow-stimulating activity (aromatic bitter) and explain traditional use in dyspeptic complaints.
- [1]MonographEMA HMPC — European Union herbal monograph on Salvia officinalis L., folium(accessed: 2026-05-19)
- [2]MonographEMA HMPC — European Union herbal monograph on Salvia officinalis L., aetheroleum(accessed: 2026-05-19)
- [3]MonographKommission E — Salviae folium (Bundesanzeiger Nr. 90, 15.05.1985, positive Monographie)(accessed: 2026-05-19)
- [4]MonographESCOP Monograph — Salviae officinalis folium(accessed: 2026-05-19)
- [6]MonographPlants For A Future — Salvia officinalis(accessed: 2026-05-19)
- [7]MonographHeilkräuter-Lexikon — Salbei(accessed: 2026-05-19)
- [8]MonographASPCA Animal Poison Control — Sage (Salvia officinalis): Non-Toxic to Dogs, Non-Toxic to Cats, Non-Toxic to Horses(accessed: 2026-08-10)
- [9]MonographCliniTox Giftpflanzen — Salvia officinalis L.: schwach giftig (+) (Institut für Veterinärpharmakologie und -toxikologie, Universität Zürich)(accessed: 2026-08-10)
- [5]BookMadaus, Gerhard: Lehrbuch der biologischen Heilmittel, Bd. III — Salvia officinalis (1938, PD)(accessed: 2026-05-19)
Distribution in Europe
🪴 Grow at home
- ☀ Light
- full sun
- 💧 Water
- weekly
- 🌱 Soil
- Sandy with drainage
- 🪴 Pot
- 20 cm
- ⭐ Difficulty
- ★☆☆ beginner
- 🐾 Pets
- non-toxic — verified against the ASPCA list
Tips:
- Very robust — tolerates drought, heat, poor soil.
- Full sun perfect — otherwise leaves go soft.
- Replace every 3-4 years, old plants get woody.
Care tips are general indoor-gardening recommendations, not scientific sources.
🤝 Permaculture Partners
In your garden, this plant acts as:
✨ Best symbiotic partners
- 🌿 Carrot Classic companion-planting partner.
- 🌿 Lavandula angustifolia Classic companion-planting partner.
- 🌿 Matricaria chamomilla Classic companion-planting partner.
- 🌿 Oregano Classic companion-planting partner.
- 🌿 Rosemary Mediterranean dry alliance — same needs.
- 🌿 Thymus vulgaris Both aromatic and drought-tolerant — herb-spiral classic.
🌟 Neutral neighbours
⚠️ Better not planted together
📦 Part of these planting sets:
Source: Helga und Margarete Langerhorst, Mein gesunder Naturgarten (eigene Kuration)