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Salix alba
CautionSilber-Weide · (Salix alba)
Willow family (Salicaceae)
Description
Growing tall along riverbanks and damp ground, this tree with silvery shimmering leaves belongs to the willow family (Salicaceae). The bark of young branches, stripped in spring, is used — it is rich in salicin and related salicyl alcohol ester glycosides, precursor substances converted to salicylic acid in the body. Commission E recognises willow bark tea and tincture as a traditional remedy for fever, mild joint complaints and pain. IMPORTANT: anyone with known hypersensitivity to acetylsalicylic acid (aspirin) or other NSAIDs faces a risk of cross-reactivity, and children under 12 must not take salicylates during viral infections (Reye syndrome risk). Per EMA, use should not exceed four weeks without medical supervision; willow bark is considered contraindicated in pregnancy and breastfeeding.
🌿 Risk of confusion — read before wild-harvesting!
SALICYLATE SENSITIVITY: Willow bark contains salicin (a salicylate precursor metabolised to salicylic acid). Cross-reactivity is possible with acetylsalicylic acid (aspirin) or other NSAIDs — AVOID willow bark if sensitive. REYE SYNDROME: Children and adolescents under 12 with viral infections (influenza, chickenpox) must not take salicylates — life-threatening risk. GASTROINTESTINAL: Take after meals if peptic ulcer, gastritis or NSAID-sensitive GI tract is known; discontinue and consult a doctor for severe stomach pain. DURATION: Short-term use; per EMA maximum 4 weeks without medical supervision. Chronic joint disease requires medical management. PAIN AS SIGNAL: Pain is a warning — identify the cause before prolonged symptomatic treatment.
CONTRAINDICATED during pregnancy
Willow bark is contraindicated in pregnancy, especially the third trimester: salicylates inhibit prostaglandin synthesis, may cause premature closure of the ductus arteriosus, delay labour and increase bleeding risk. EMA and ESCOP explicitly advise: do NOT use during pregnancy.
CONTRAINDICATED during breastfeeding
Salicylates pass into breast milk and may cause cumulative effects in infants. EMA and ESCOP advise: do NOT use during lactation.
CONTRAINDICATED for children
Children under 12: CONTRAINDICATED for fever associated with viral infections (Reye syndrome risk — life-threatening). Adolescents 12–18: medical supervision only, as Reye syndrome risk persists with viral infections. Fever in children always requires medical assessment.
Critical drug interactions with:
Antikoagulanzien / Thrombozytenaggregationshemmer (Warfarin, Phenprocoumon, Clopidogrel, ASS) · Nichtsteroidale Antirheumatika (Ibuprofen, Diclofenac, Naproxen) · Methotrexat (MTX)
Decoction of willow bark (standardised to salicin) for low back pain, mild joint complaints and fever — positively assessed by Commission E; the EMA monograph lists the decoction as traditional use.
Preparation & dosage
DECOCTION (Commission E / EMA traditional use): 2–3 g of coarsely cut dried willow bark (Salix alba, S. purpurea or S. daphnoides) in 200–250 ml cold water, bring slowly to a boil, simmer 10–15 min, strain. Take 3× daily freshly prepared. Daily dose standardised to 60–120 mg total salicin. EMA indications: short-term relief of low back pain, mild joint pain and fever. Maximum 4 weeks without medical advice. Take after a meal if gastrointestinal sensitivity is known.
- Dry amount
- 2–3 g
- Doses per day
- 3×
- Max duration
- 4 weeks
⚠ Age restriction: ≥ 12 years — Not for children under 12 with fever (Reye syndrome risk, analogous to acetylsalicylic acid). Per EMA monograph: adults and adolescents from 12 years.
Willow bark tincture for rheumatic complaints, fever and headache — positive Kommission E assessment.
Preparation & dosage
TINCTURE (DER 1:5 in 25–40 % ethanol): 2–4 ml (~40–80 drops) 3× daily diluted in water. Daily dose corresponds to approx. 60–120 mg total salicin. Kommission E positive for fever, rheumatic complaints and headache. Tincture extracts phenolic glycosides slightly more efficiently than decoction. Maximum 4 weeks without medical supervision; avoid on empty stomach if gastric sensitivity known.
- Liquid amount
- 2–4 ml
- Doses per day
- 3×
- Max duration
- 4 weeks
⚠ Age restriction: ≥ 12 years — Not for children under 12 with fever (Reye syndrome risk). Due to ethanol content, avoid with alcohol dependence or liver disease.
Traditional cold macerate of willow bark — folk alternative to decoction for mild fever and cold-related headache; gentler on the stomach.
Preparation & dosage
COLD INFUSION (traditional): 1–2 g coarsely cut willow bark in 200 ml cold water, macerate 8 hours, strain, warm to drinking temperature or drink cold. Some traditional sources prefer cold maceration as it extracts tannins more gently and is considered less stomach-irritating. 2× daily. Traditional use for mild cold-related fever and headache. Preferred over hot decoction for gastric sensitivity.
- Dry amount
- 1–2 g
- Doses per day
- 2×
- Max duration
- 2 weeks
Willow bark bath for rheumatic complaints and muscle tension — external astringent and mildly anti-inflammatory folk remedy.
Preparation & dosage
BATH PREPARATION: 200–300 g dried willow bark in 3 litres cold water, bring to boil, simmer 20 min, strain. Add concentrate to bathwater (approx. 37–38 °C). Bathe 15–20 minutes. Folk use for rheumatic joint complaints, muscle tension and sweaty feet (astringent effect of tannins). External use avoids gastrointestinal issues. Dry and warm skin thoroughly after. Do not apply to open wounds or irritated skin.
- Dry amount
- 200–300 g
- Doses per day
- 1×
- Max duration
- 2 weeks
External rubbing with willow bark tincture for local joint and muscle pain — folk use based on percutaneous salicin absorption and ethanol stimulation.
Preparation & dosage
RUBBING TINCTURE (external, undiluted or diluted 1:1): Apply 5–10 ml willow bark tincture (1:5 in 40–70 % ethanol) to affected joints or muscles and massage gently. Use 2× daily; wash after application. Folk external use for painful joints and muscles. Effect based on ethanol stimulation and mild percutaneous salicin absorption. Do not apply to open or irritated skin.
- Liquid amount
- 5–10 ml
- Doses per day
- 2×
- Max duration
- 4 weeks
Folk medicinal leaf tea of white willow for mild colds and fever — weaker effect than bark decoction, rich in flavonoids and tannins.
Preparation & dosage
LEAF INFUSION: 1–2 tsp dried willow leaves in 200 ml boiling water, covered, steep 10 min, strain. 2× daily between meals. Lower salicin content than bark — milder effect. Folk use for mild colds and fever. Also contains flavonoids and tannins. Limit use to 2 weeks; prefer bark decoction if effect is insufficient.
- Dry amount
- 1–2 g
- Doses per day
- 2×
- Max duration
- 2 weeks
Willow bark decoction as compress for minor wounds, eczema and irritated skin — astringent and mildly anti-inflammatory folk medicine.
Preparation & dosage
COMPRESS: Boil 20–30 g willow bark in 500 ml water, simmer 15 min, cool, strain. Soak a clean linen cloth in the lukewarm decoction, wring out, apply to affected skin (poorly healing minor wounds, eczema, itchy skin). 2× daily, 15–20 minutes each time. Astringent tannins provide anti-inflammatory and contracting effect. If signs of infection or worsening: consult a doctor.
- Dry amount
- 20–30 g
- Doses per day
- 2×
- Max duration
- 2 weeks
SALICYLATE SENSITIVITY: Willow bark contains salicin (a salicylate precursor metabolised to salicylic acid). Cross-reactivity is possible with acetylsalicylic acid (aspirin) or other NSAIDs — AVOID willow bark if sensitive. REYE SYNDROME: Children and adolescents under 12 with viral infections (influenza, chickenpox) must not take salicylates — life-threatening risk. GASTROINTESTINAL: Take after meals if peptic ulcer, gastritis or NSAID-sensitive GI tract is known; discontinue and consult a doctor for severe stomach pain. DURATION: Short-term use; per EMA maximum 4 weeks without medical supervision. Chronic joint disease requires medical management. PAIN AS SIGNAL: Pain is a warning — identify the cause before prolonged symptomatic treatment.
Willow bark is contraindicated in pregnancy, especially the third trimester: salicylates inhibit prostaglandin synthesis, may cause premature closure of the ductus arteriosus, delay labour and increase bleeding risk. EMA and ESCOP explicitly advise: do NOT use during pregnancy.
Salicylates pass into breast milk and may cause cumulative effects in infants. EMA and ESCOP advise: do NOT use during lactation.
Children under 12: CONTRAINDICATED for fever associated with viral infections (Reye syndrome risk — life-threatening). Adolescents 12–18: medical supervision only, as Reye syndrome risk persists with viral infections. Fever in children always requires medical assessment.
Drug interactions
Antikoagulanzien / Thrombozytenaggregationshemmer (Warfarin, Phenprocoumon, Clopidogrel, ASS)
Salicylates from willow bark additively enhance the anticoagulant and antiplatelet effect of warfarin, phenprocoumon and clopidogrel — increased bleeding risk (gastrointestinal bleeds, haematomas). Avoid combination or use only under strict INR monitoring and medical supervision.
Nichtsteroidale Antirheumatika (Ibuprofen, Diclofenac, Naproxen)
Additive COX-inhibiting and mucosal irritating effect when combining willow bark with NSAIDs — increased risk of gastrointestinal bleeding and renal dysfunction. Avoid combination.
Methotrexat (MTX)
Salicylates may inhibit renal excretion of methotrexate and raise its plasma levels — risk of methotrexate toxicity (bone marrow suppression, mucositis). Combination contraindicated without close medical monitoring.
Antidiabetika (Sulfonylharnstoffe, Insulin)
High salicylate doses may lower blood glucose and potentiate antidiabetic drugs — hypoglycaemia risk. Rarely clinically significant at therapeutic willow bark doses, but monitor blood glucose.
Kortikosteroide (Prednison, Prednisolon, Dexamethason)
Corticosteroids increase renal salicylate clearance, reducing plasma levels. Abrupt withdrawal of corticosteroids may cause salicylate levels to rise. Additionally additive gastrointestinal side-effect risk.
Contraindications
- Hypersensitivity to salicylates or non-steroidal anti-inflammatory drugs (NSAIDs) — cross-reactivity possible.
- Pregnancy (especially third trimester): prostaglandin inhibition, premature closure of ductus arteriosus, increased bleeding risk.
- Lactation: salicylates pass into breast milk.
- Children under 12 with fever or viral infections (Reye syndrome risk).
- Active peptic ulcers (gastric or duodenal ulcer).
- Severe hepatic or renal impairment — salicylate accumulation possible.
Harvested part: bark of young branches
- Time of day:
- Spring — ideally March to April when buds swell and sap rises but leaves have not yet broken out. At this stage bark peels most easily and salicin content is highest. Harvest in the morning after dew evaporates but before midday heat.
- Drying:
- Use only bark from 2–4-year-old shoots — smooth, grey-green young bark with highest active content; old furrowed bark contains less salicin and more tannins. Peel bark in strips (do not ring-bark — kills the tree!), harvest at most 1/3 of the branches of any single tree. Dry strips on cloth or racks at max. 40 °C in shade or dehydrator — bark snaps when ready. Store airtight in dark containers, cool and dry. Shelf life: 1–2 years under optimal conditions. Check salicin content before use: if taste is flat (low bitterness), discard.
- Storage:
- 18 months — Airtight, dark, dry, cool (below 25 °C). Salicin content declines with moisture and heat. Use within 12–18 months.
- Time of day:
- May to June — harvest young, fully expanded leaves before summer heat sets in. Collect on dry mornings after dew has evaporated. Young leaves contain more flavonoids and fewer tannins than older leaves in midsummer.
- Drying:
- Spread leaves individually or in thin layer on cloths or drying racks. Shade-dry at 35–40 °C with good air circulation; turn regularly until leaves are completely dry and slightly brittle (approx. 2–5 days depending on humidity). Do not dry in direct sunlight — UV degrades flavonoids. Store in dark containers or paper bags.
- Storage:
- 12 months — Dry, dark, cool. Use within 1 year — flavonoid loss thereafter. Do not store in plastic bags (moisture).
- Salicin (Salicoylalkohol-Glucosid)GlycosideContent: 1-11 %Bark
Lead compound of willow bark. Phenolic glucoside hydrolysed in the gut to saligenin and glucose, then oxidised in the liver to salicylic acid. Anti-inflammatory, antipyretic and analgesic; slower onset and better tolerated than aspirin as it is not a direct COX inhibitor. EMA standardisation on total salicin (min. 1.5 % per Ph. Eur. or 60–120 mg per daily dose).
- Salicylalkohol-Ester-Glycoside (Salicortin, Tremulacin, Fragilin)GlycosideContent: 2-8 %Bark
Acetylated salicin derivatives that also release salicylic acid upon metabolism. Quantified together with salicin as 'total salicins'. Salicortin is quantitatively significant in S. alba bark; tremulacin dominates in S. tremula and S. purpurea. All contribute to the overall effect of willow bark.
- Flavonoide (Naringenin, Luteolin-7-glucosid, Quercetin, Isoquercitrin)FlavonoidContent: 0.5-2 %Bark
Antioxidant and mildly anti-inflammatory. Complement the analgesic and antipyretic main effect of salicyl glycosides. Contribute to inhibition of the arachidonic acid cascade (5-LOX and COX). Higher concentrations in bark of younger shoots (1–3 years) than in old bark.
- Kondensierte Gerbstoffe (Catechingerbstoffe, Proanthocyanidine)TanninContent: 5-20 %Bark
Quantitatively the most abundant constituent group in the bark; responsible for astringency. Locally inhibit inflammatory mediators and protect mucous membranes when applied externally. When taken orally: tannins may inhibit iron absorption — do not take willow bark tea immediately with iron-rich meals.
- Phenolcarbonsäuren (p-Cumarsäure, Kaffeesäure, Chlorogensäure)Phenolic acidContent: 0.5-1.5 %Bark
Antioxidant and mildly anti-inflammatory; complement salicyl glycosides and flavonoids. Chlorogenic acid inhibits cyclooxygenase in vitro. No significant stand-alone pharmacological effect at therapeutic doses.
- Catechin und Epicatechin (monomere Flavan-3-ole)TanninContent: 0.5-3 %Bark
Monomeric precursors of proanthocyanidins. Antioxidant, mildly antibacterial and capillary-protective. Contribute to overall astringency of bark, particularly in external applications (compresses, baths).
- Minerale (Kalium, Calcium, Mangan, Silicium — Spuren)MineralContent: SpurenBark
Trace minerals without independent pharmacological significance at therapeutic doses. Potassium and calcium part of plant matrix; manganese and silicon detectable in tannin-rich barks. Relevant only in a nutritional context.
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- [2]MonographESCOP Monographs — Salicis cortex (Willow Bark), 2nd edition (incl. supplement 2009)(accessed: 2026-05-21)
- [3]MonographKommission E — Salicis cortex (Weidenrinde), Monographie (positiv), BAnz Nr. 228, 1992(accessed: 2026-05-21)
- [6]MonographPlants For A Future (PFAF) — Salix alba database entry(accessed: 2026-05-21)
- [4]BookWichtl, Max (Hrsg.) — Teedrogen und Phytopharmaka: Ein Handbuch für die Praxis auf wissenschaftlicher Grundlage, 5. Auflage. Salicis cortex. Wissenschaftliche Verlagsgesellschaft Stuttgart, 2009.(accessed: 2026-05-21)
- [5]BookMadaus, Gerhard — Lehrbuch der biologischen Heilmittel, Band II: Salix (Weide), 1938 (Public Domain)(accessed: 2026-05-21)
- [7]WikipediaSilber-Weide — Medizinische Verwendung (Wikipedia DE)(accessed: 2026-05-21)
- [8]WikipediaSalix alba — Uses and Pharmacology (Wikipedia EN)(accessed: 2026-05-21)