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Sambucus nigra
Caution🐾Schwarzer Holunder · (Sambucus nigra)
Moschatel family (Adoxaceae)
Description
Creamy-white, strongly fragrant flower clusters in May and June and deep black, glossy berries in September and October identify black elder, a shrub of the moschatel family. The flowers contain flavonoids such as rutin and isoquercitrin, essential oil and mucilage, while the berries are rich in anthocyanins and polyphenols. Recognised use includes the flowers as tea, gargle or tincture for cold symptoms of the airways and to support the immune system; the ripe berries, always thoroughly cooked, are used similarly in folk practice and as a flavourful ingredient. Crucially, all other plant parts – leaves, bark, roots and unripe berries – contain the cyanogenic glycoside sambunigrin and are toxic raw; even ripe berries must be simmered for at least 15 minutes before eating. Seek medical advice for high fever, breathing difficulty, or symptoms lasting more than seven days.
🌿 Risk of confusion — read before wild-harvesting!
TOXICITY ALERT — confusion risk and raw-consumption risk: Only FLOWERS (Sambuci flos) are the recognised medicinal drug.
Traditional diaphoretic flower tea for feverish colds — perspiration-promoting use recognised by EMA as traditional use.
Preparation & dosage
DIAPHORETIC TEA: 1.5–3 g dried elder flowers in 150 ml boiling water, covered, steep 5–10 min, strain. 2–3× daily as HOT as tolerable — most effective in the evening; wrap up warm afterwards. Supports perspiration during feverish colds (rhinitis, flu). Max 1 week per EMA monograph (traditional use, revision 2018). Seek medical attention for fever above 39 °C, dyspnoea, purulent sputum, or symptoms lasting more than 7 days.
- Dry amount
- 1.5–3 g
- Doses per day
- 3×
- Max duration
- 1 weeks
⚠ Age restriction: ≥ 12 years — Per EMA, only from 12 years. Insufficient safety data for children under 12.
Elder flower cold tea for catarrhs of the upper respiratory tract and bronchitis — Kommission E positive monograph (1992): diaphoretic and mucous membrane soothing.
Preparation & dosage
COLD TEA (Kommission E): 3–5 g elder flowers in 250 ml hot water, covered, steep 10 min, strain. Daily dose 10–15 g. 2–3 hot cups daily for early colds, catarrhs of the upper respiratory tract, and bronchitis. Often blended with linden flowers or thyme. Max 1 week.
- Dry amount
- 3–5 g
- Doses per day
- 3×
- Max duration
- 1 weeks
⚠ Age restriction: ≥ 12 years — Per Kommission E and EMA from 12 years. Under 12: consult doctor.
Elder flower gargle for sore throat and hoarseness — mildly anti-inflammatory and mucous membrane soothing.
Preparation & dosage
GARGLE: 2–3 g dried elder flowers in 150–200 ml boiling water, covered, steep 10 min, strain, cool to hand-warm (~40 °C). Gargle thoroughly 30–60 seconds 2–3× daily (do not swallow) for sore throat, hoarseness, and oral mucous membrane inflammation. Folk use also as a wash for conjunctivitis (compresses, 1–2× daily).
- Dry amount
- 2–3 g
- Doses per day
- 3×
- Max duration
- 1 weeks
⚠ Age restriction: ≥ 12 years — From 12 years. Young children cannot gargle safely.
Elder flower tincture as a convenient alternative to the sweating tea for colds — diaphoretic, established in folk medicine.
Preparation & dosage
ELDER FLOWER TINCTURE (DER 1:5 in 25 % ethanol): 2–4 ml (~40–80 drops) 3× daily diluted in a glass of warm water or herbal tea. Folk alternative to the tea when preparation is inconvenient; similarly diaphoretic. Note ethanol content — avoid in children, pregnancy, alcohol or liver disease. Consult doctor if symptoms persist beyond 7 days.
- Liquid amount
- 2–4 ml
- Doses per day
- 3×
- Max duration
- 1 weeks
⚠ Age restriction: ≥ 18 years — Due to ethanol content adults only. Children and adolescents under 18: prefer the tea preparation.
Elderberry syrup from thoroughly cooked ripe berries — traditional household remedy for colds and immune support. Raw berries toxic.
Preparation & dosage
ELDERBERRY SYRUP: Use only fully ripe, deep black berries (September–October, NEVER raw). Simmer 500 g de-stemmed, washed berries in 250 ml water 15–20 minutes (destroys sambunigrin), press through sieve. Boil juice with 300–400 g sugar and optional spices (cinnamon, cloves, lemon peel), bottle in sterile jars. 1–2 tbsp daily neat or diluted in hot water. Folk use: supportive in colds, immune support, hoarseness. Raw berries are TOXIC — thorough cooking mandatory!
Elderberry decoction as a simple folk remedy for colds — anthocyanins and flavonoids retained; sambunigrin inactivated by boiling.
Preparation & dosage
BERRY DECOCTION: 5–10 g dried elderberries in 300 ml cold water, bring to boil and simmer 15–20 minutes (decoction mandatory — boiling inactivates sambunigrin), strain. 1–2 cups daily, sweeten with honey if desired. Folk use in colds, sore throat, winter immune support. Anthocyanins are largely retained during cooking.
- Dry amount
- 5–10 g
- Doses per day
- 2×
- Max duration
- 2 weeks
Elder flower bath and steam inhalation for cold symptoms and skin care — relaxing and mildly diaphoretic.
Preparation & dosage
ELDER FLOWER BATH: 50–100 g dried elder flowers in 2 litres boiling water, steep 15 min, strain, add to full bath (37–38 °C, not hotter). Soak 15–20 min. Folk use for colds (steam bath for face also possible: bowl with hot infusion, towel over head), dry skin, joint complaints. For steam inhalation: 2–3 tbsp flowers in 1 L hot water, inhale 5–10 min.
- Dry amount
- 50–100 g
- Doses per day
- 1×
- Max duration
- 2 weeks
Elder flowers in the kitchen — cordial, syrup, fritters and vinegar; Central European classic. Flowers contain NO sambunigrin and can be used fresh or dried.
Preparation & dosage
KITCHEN (elder flowers): Fresh flower umbels (May–June) for elderflower cordial/syrup: cold-infuse umbels with lemon slices and sugar 24 hours, strain (no boiling needed — flowers contain no sambunigrin). For 'Hollerküchle' (Holunder fritters): dip whole fresh umbel in batter, deep-fry. Elder flower vinegar: steep fresh flowers in apple vinegar 2 weeks. Cordial is a classic summer drink in Central European cuisine. Dried flowers as flavouring in desserts, panna cotta, lemonade.
TOXICITY ALERT — confusion risk and raw-consumption risk: Only FLOWERS (Sambuci flos) are the recognised medicinal drug. All other plant parts (leaves, bark, roots, unripe berries, seeds) contain the cyanogenic glycoside sambunigrin, which releases hydrogen cyanide in the body — TOXIC; symptoms: nausea, vomiting, diarrhoea, dizziness, in large quantities convulsions. Ripe black berries contain lower sambunigrin levels but MUST ALWAYS BE THOROUGHLY COOKED (simmer at least 15 min) — raw consumption of even ripe berries in quantity can cause poisoning. Do not confuse with dwarf elder (Sambucus ebulus, poisonous!) — it has characteristically horizontal stems and strongly smelling foliage. Seek medical attention for fever above 39 °C, dyspnoea, purulent sputum, or symptoms lasting over 7 days. Consult doctor before taking elderberry products with autoimmune diseases or immunosuppressive therapy.
⏱ Max continuous use: 1 weeks
Elder flower tea in therapeutic doses not recommended during pregnancy due to insufficient safety data (EMA monograph). Occasional culinary use (flower cordial in moderation) considered safe. Elderberry products in pregnancy: avoid — no data.
Therapeutic doses not recommended during lactation due to lack of data (EMA). Culinary use of flower cordial and well-cooked berry products in household amounts considered safe.
Elder flower tea per EMA only from 12 years (no safety data for younger children). Children must NEVER eat raw berries — sambunigrin poisoning risk. Well-cooked berry products (syrup, puree, jam) in child-appropriate amounts considered safe. Always seek medical advice for fever in children under 12.
Drug interactions
Immunsuppressiva (Ciclosporin, Tacrolimus, Methotrexat, Azathioprin, Kortikosteroide)
Elderberry preparations (syrup, extracts) show immunostimulating properties in vitro and in animal studies (stimulation of cytokines IL-1β, TNF-α, IL-6 via anthocyanins and polysaccharides). Theoretically may reduce efficacy of immunosuppressants. No clinical data in humans; caution in transplant patients or active autoimmune disease (lupus, RA, MS).
Antidiabetika (Insulin, Metformin, Sulfonylharnstoffe, SGLT-2-Hemmer)
Elderberry extracts show hypoglycaemic properties in some studies (alpha-glucosidase inhibition, improved insulin sensitivity via anthocyanins). Theoretically additive blood glucose lowering with antidiabetic drugs — hypoglycaemia risk. Monitor blood glucose regularly; discuss dose adjustment with treating physician.
Diuretika (Thiazide, Schleifendiuretika, kaliumsparende Diuretika)
Elder flowers traditionally have mild diuretic properties. Theoretical additive effect with diuretics — risk of excessive fluid and electrolyte loss (dehydration, hypokalaemia). Ensure adequate fluid intake; monitor electrolytes if needed.
Contraindications
- Hypersensitivity (allergy) to black elder (Sambucus nigra) or other Adoxaceae/Caprifoliaceae.
- Children under 12 years (therapeutic preparations per EMA — culinary berry products excepted).
- Consumption of raw or unripe berries, or raw leaves, bark, and roots in any amount — sambunigrin (cyanogenic glycoside) poisoning.
- Pregnancy and lactation (therapeutic doses) — avoid due to insufficient safety data.
- Severe immunosuppression or active autoimmune disease (elderberry products may stimulate immune activity — medical consultation required).
Harvested part: flowers (May-June) and ripe berries (Sept-Oct)
- Time of day:
- Dry, sunny morning (9–12), once dew has fully evaporated — flavonoid and essential oil content highest then. Harvest umbels when fully open and still cream-white (browning umbels = past optimal harvest time).
- Drying:
- Pick fully opened cream-white flower umbels in dry weather. Do NOT rinse with water (removes pollen and volatile constituents). Keep stems as short as possible or remove entirely — thicker stems contain sambunigrin (not in flowers themselves, but contamination risk). Spread loosely in a single layer on clean cloths or racks in shade at max 35–40 °C, or hang upside down. After drying, strip individual florets from the thin stem tips — the florets are the drug. Harvest window narrow: elder flowering lasts only 10–14 days depending on location and year.
- Storage:
- 12 months — Airtight in dark glass jars or tins at room temperature, dry. Use within 12 months — flavonoid content declines thereafter. Discard if musty or browned.
- Time of day:
- Dry days in late summer to early autumn (August–October) — harvest berries when fully ripe, glossy deep black-violet, in whole fruiting clusters. Ideally after the first light frost (anthocyanin content increases, flavour milder). Green or reddish berries are unripe and have higher sambunigrin content — NEVER harvest unripe berries.
- Drying:
- Wash berries and strip from stems (stems contain sambunigrin). Use fresh (syrup, puree — cook immediately and thoroughly, simmer min 15 min) or dehydrate at 50–60 °C for 10–16 hours until leathery. Dried berries for tea (decoction) — always boil, never merely steep. For tincture: fresh ripe berries 1:5 in 40–50 % ethanol (ethanol also inactivates sambunigrin).
- Storage:
- 12 months — Dried berries: airtight, cool, dark, dry — use within 12 months. Fresh berries very perishable (max 2–3 days refrigerated); better processed directly into syrup or puree. Syrup: sterile bottled and refrigerated, keeps 6–12 months.
- Flavonoide (Rutin, Isoquercitrin, Hyperosid, Astragalin, Quercetin-3-O-glucosid)FlavonoidContent: 0,8-3 %Flower
Lead compound group of the flowers (Sambuci flos). Rutin and isoquercitrin predominate. Responsible for diaphoretic and mildly anti-inflammatory action; improve capillary resistance and act as antioxidants. EMA monograph recognises efficacy based on this fraction.
- Anthocyane (Cyanidin-3-O-glucosid, Cyanidin-3-O-sambubiosid, Cyanidin-3-O-rutinosid)FlavonoidContent: 0,2-1 %Fruit
Main pigments of the ripe berries, responsible for the deep black-violet colour. Strongly antioxidant (high ORAC value), antiviral activity described in vitro (inhibition of influenza haemagglutinin-neuraminidase). Immunostimulating effect (cytokine stimulation) in cell culture experiments. Clinical efficacy data in humans remain limited.
- Sambunigrin (cyanogenes Glykosid)GlycosideContent: 0,01-0,1 %Leaf
TOXIC — main cyanogen of black elder. Highest concentrations in leaves, bark, roots, unripe berries; lower amounts in ripe fruit (mainly seeds). Hydrolysis by plant glucosidases and gut microbiota releases hydrogen cyanide (HCN). Thermolabile — thorough cooking (≥15 min simmering) reliably inactivates sambunigrin in berry preparations. Flowers contain no sambunigrin.
- Ätherisches Öl (Blüten: Hotrienol, Linalool, α-Terpineol, Nerolidol)Essential oilContent: 0,03-0,3 %Flower
Low content; responsible for the characteristic sweet-floral scent of elder flowers. Main flower oil components: hotrienol (lead odorant of elderflower aroma), linalool, cis- and trans-linalool oxides. Pharmacologically insignificant at therapeutic concentrations; contributes to sensory quality of the drug.
- Schleimstoffe (Polysaccharide, Pektine)MucilageContent: 7-11 %Flower
Highest-content component of the flowers. Mucilaginous polysaccharides form a protective layer on irritated mucous membranes (mouth, throat, bronchi) — explains use as gargle and cold tea. Soothing for upper respiratory tract inflammation.
- Phenolsäuren (Chlorogensäure, Kaffeesäure, p-Cumarsäure)Phenolic acidContent: 0,1-0,5 %Flower
Antioxidant and mildly anti-inflammatory (COX inhibition). Complement the flavonoid action. Chlorogenic acid documented in elder flowers and berries; inhibits intestinal glucose uptake in vitro.
- Triterpene (α-Amyrin, β-Amyrin, Ursolsäure, Oleanolsäure, β-Sitosterol)OtherContent: 0,2-1 %Flower
Pentacyclic triterpenic acids with mild anti-inflammatory properties; β-sitosterol as phytosterolic companion. Contribute to the overall drug effect without independent clinical relevance at therapeutic doses.
- Polyphenole / Procyanidine (Beeren)OtherContent: 0,5-2 %Fruit
Oligomeric procyanidins (B1, B2) in the berries; complement anthocyanins as antioxidant components. Documented in raw berry extracts; total polyphenol content of ripe berries ranks among the highest of native wild fruits. Retention and bioavailability reduced after heating (syrup) but substantial fractions remain.
- [1]MonographEMA/HMPC/611512/2016 — European Union herbal monograph on Sambucus nigra L., flos, Revision 1 (Final, 27 June 2018)(accessed: 2026-05-21)
- [2]MonographKommission E — Sambuci flos (Holunderblüten), Monographie (positiv), BAnz Nr. 50, 13. März 1990, zuletzt geändert 1992(accessed: 2026-05-21)
- [3]MonographESCOP Monographs — Sambuci flos (Elderflower), 2nd edition with supplement, European Scientific Cooperative on Phytotherapy(accessed: 2026-05-21)
- [6]MonographPlants For A Future (PFAF) — Sambucus nigra database entry(accessed: 2026-05-21)
- [9]MonographCliniTox Giftpflanzen — Sambucus nigra L.: giftig + (Institut für Veterinärpharmakologie und -toxikologie, Universität Zürich)(accessed: 2026-08-10)
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- [5]BookMadaus, Gerhard — Lehrbuch der biologischen Heilmittel, Band II: Sambucus nigra (Schwarzer Holunder), 1938 (Public Domain)(accessed: 2026-05-21)
- [7]WikipediaSchwarzer Holunder (Wikipedia DE)(accessed: 2026-05-21)
- [8]WikipediaSambucus nigra (Wikipedia EN)(accessed: 2026-05-21)