© Michael Becker · CC BY-SA 3.0 · Commons
Ononis spinosa
CautionDornige Hauhechel · (Ononis spinosa)
Legume family (Fabaceae)
Description
Its namesake sharp thorns make spiny restharrow a stubborn obstacle on pastures and poor grassland soils, where it flowers with pink-violet pea-like blossoms. The part used is the root, dug in autumn, which is rich in isoflavones (formononetin, ononin, biochanin A), triterpene saponins and tannins. As tea or tincture, restharrow root is recognised by Commission E for irrigation therapy of the urinary tract and is also used in folk medicine for joint complaints. Adequate fluid intake of at least two litres daily is essential for the treatment to work, since without it the therapy remains ineffective. Restharrow must not be used for oedema caused by cardiac or renal insufficiency, as its aquaretic action can worsen the underlying condition. If fever, severe pain on urination or blood in the urine occurs, a doctor should be consulted immediately; without medical supervision, use should not exceed four weeks.
CONTRAINDICATED during pregnancy
Do not use in pregnancy. Animal and in vitro data show uterine-stimulating potential of constituents (isoflavones, ononidin); additionally no adequate clinical safety data. Kommission E and EMA do not recommend use in pregnancy.
CONTRAINDICATED during breastfeeding
Do not use during lactation — insufficient safety data; transfer of isoflavones into breast milk cannot be excluded.
Classic irrigation therapy using restharrow root infusion for inflammatory urinary tract complaints and prevention of kidney gravel — positively assessed by Kommission E and EMA (traditional use).
Preparation & dosage
INFUSION (Kommission E, EMA traditional use): 2–3 g of coarsely chopped dried restharrow root (Ononidis radix) in 250 ml boiling water, covered, steep 15 min, strain. Prepare fresh each time. 2–3 cups daily, preferably between meals. Daily dose: 6–9 g drug. For irrigation therapy in inflammatory conditions of the urinary tract and to prevent kidney gravel. IMPORTANT: Drink plenty of fluids (at least 2 litres daily) — the plant acts as an aquaretic, increasing urine volume. Duration up to 4 weeks; persistent symptoms or fever require medical evaluation.
- Dry amount
- 2–3 g
- Doses per day
- 3×
- Max duration
- 4 weeks
Traditional restharrow root tincture as an alternative to tea — liquid dosage form for urinary irrigation therapy.
Preparation & dosage
TINCTURE (DER 1:5 in 45–60 % ethanol): 2–4 ml (~40–80 drops) 3× daily, taken with ample water. Equivalent to ~6–9 g drug per day. Drink liberally alongside (at least 2 litres daily) — the aquaretic effect requires adequate fluid intake. Traditional alternative to tea for urinary irrigation therapy. Duration up to 4 weeks.
- Liquid amount
- 2–4 ml
- Doses per day
- 3×
- Max duration
- 4 weeks
Folk use for gout and rheumatic complaints — the aquaretic effect is traditionally held to support uric acid elimination; evidence is traditional only.
Preparation & dosage
FOLK USE FOR GOUT/RHEUMATISM: Infusion as for urinary indication (2–3 g root, 250 ml boiling water, 15 min covered, strain). 2× daily, alongside increased fluid intake. Folk use for supporting elimination of uric acid in gout and rheumatic complaints. Efficacy for this indication is not documented by modern clinical studies — traditional use only. Not a substitute for medically prescribed gout therapy.
- Dry amount
- 2–3 g
- Doses per day
- 2×
- Max duration
- 3 weeks
Folk flower tea as a mild alternative to the root — lower in active constituents, less scientific evidence, used as an adjunct.
Preparation & dosage
FLOWER TEA (folk): 1.5–2 g dried restharrow flowers in 200 ml hot water, covered, steep 10 min, strain. 2× daily. Folk use as a milder alternative to the root — lower active constituent concentration. Less well documented than root preparations; Kommission E and EMA assessed only the root positively. For urinary complaints, prefer root preparations.
- Dry amount
- 1.5–2 g
- Doses per day
- 2×
- Max duration
- 2 weeks
Folk restharrow root bath for rheumatic complaints and skin conditions — external use, not officially assessed.
Preparation & dosage
FULL / PARTIAL BATH (folk): 50–100 g dried restharrow root in 2–3 litres cold water, simmer 20–30 min (decoction), cool, strain into bath water. Bath temperature 36–38 °C, duration 15–20 minutes, 2–3× weekly. Folk use for rheumatic complaints, skin rashes and pruritic skin conditions as hip or full bath. External use is not assessed by Kommission E or EMA; traditional use only.
Restharrow root as a component of bladder and kidney tea blends (e.g. DAB bladder tea) — synergistic aquaretic effect with birch leaf, goldenrod and horsetail.
Preparation & dosage
HERBAL BLEND: Restharrow root is traditionally a component of bladder and kidney tea blends (Blasentee, DAB Nr. 8 blend). Typical combination: restharrow root + birch leaf + goldenrod herb + horsetail, equal parts. 1 tbsp (~5 g) blend per 250 ml, steep 15 min, 3× daily. Synergistic aquaretic effect of all components. Officially established in phytotherapy (DAB, NRF formulations).
- Dry amount
- 2–3 g
- Doses per day
- 3×
- Max duration
- 4 weeks
Standardised restharrow root extracts as phytopharmaceuticals — officially approved dosage form for irrigation therapy (Kommission E positive).
Preparation & dosage
LIQUID / STANDARDISED EXTRACT: Dry and liquid extracts (DER 3–6:1, ethanol 40–60 %) are approved as phytopharmaceuticals. Daily equivalent: 6–9 g drug. Proprietary preparations (e.g. Cysto Fink, Hepaselect, combination kidney-bladder teas) dose per manufacturer instructions. Drink ample fluid (≥ 2 l/day). Not longer than 4 weeks without medical supervision. Kommission E positive assessment for urinary irrigation therapy.
- Liquid amount
- 2–5 ml
- Doses per day
- 3×
- Max duration
- 4 weeks
IRRIGATION THERAPY ONLY WITH ADEQUATE FLUID INTAKE: Drink at least 2 litres of fluid daily — without sufficient fluid intake the irrigation therapy is ineffective and counterproductive. CONTRAINDICATION oedema: Do NOT use if oedema is caused by cardiac or renal insufficiency — aquaretic therapy may worsen the underlying condition. Fever, severe pain on urination or blood in urine: seek medical attention immediately — possible serious underlying cause (kidney stones, pyelonephritis). Self-treatment of suspected kidney stones without medical assessment not advised. Self-treatment of chronic urinary infections without diagnosis is not recommended. Limit use to 4 weeks without medical supervision.
Do not use in pregnancy. Animal and in vitro data show uterine-stimulating potential of constituents (isoflavones, ononidin); additionally no adequate clinical safety data. Kommission E and EMA do not recommend use in pregnancy.
Do not use during lactation — insufficient safety data; transfer of isoflavones into breast milk cannot be excluded.
Not recommended for children under 12 years — insufficient clinical safety data. EMA and Kommission E provide no paediatric dosages.
Drug interactions
Diuretika (Furosemid, Thiazide, Spironolacton)
Restharrow root has a mild aquaretic effect (increases urinary output). Concurrent use with diuretics may additively increase fluid and electrolyte losses. Risk of hyponatraemia, hypokalaemia and dehydration. Monitor fluid and electrolyte balance.
Lithium
Increased urinary output from aquaretic constituents may affect renal lithium excretion and alter serum lithium levels (risk of both lithium accumulation and sub-therapeutic levels depending on baseline metabolism). Lithium level monitoring recommended.
Antikoagulantien / Gerinnungshemmer (Cumarin-Derivate: Phenprocoumon, Warfarin)
Restharrow contains isoflavones with weak oestrogenic activity and phenolic compounds; theoretical interaction with vitamin K metabolism or clotting cascade not fully excluded. Not clinically documented, but caution with oral anticoagulants — INR monitoring advisable.
Contraindications
- Oedema resulting from cardiac or renal insufficiency — aquaretic irrigation therapy is contraindicated in these conditions.
- Impaired renal function (renal insufficiency) — increased urine production may place additional strain on the kidneys; use only after medical consultation.
- Hypersensitivity to Ononis spinosa or other Fabaceae (legumes).
- Pregnancy and lactation (see pregnancy/lactation notes).
- Acute kidney inflammation (pyelonephritis, glomerulonephritis) — acute febrile infections require medical treatment first; irrigation therapy only adjunctive and after diagnosis.
Harvested part: root (autumn)
- Time of day:
- Harvest in early autumn (September–November) or in early spring before new growth (March) on dry days preferred. Roots are obtained by digging — at this time the active constituents (isoflavones, saponins) are most concentrated.
- Drying:
- After digging, free roots from soil and rootlets, wash and cut into 3–5 cm pieces (longitudinal cut facilitates drying). Dehydrator at 40–50 °C or on cloth in a shaded, well-ventilated spot below 40 °C ambient. Drying time 2–4 days (dehydrator) or 7–14 days (air-drying). The root is dry when it snaps crisply and is hard throughout — no soft spots (mould risk). Purchase from pharmacy trade is preferable as digging is labour-intensive and confusions with toxic neighbour plants are avoided. NOTE: Spiny restharrow is protected or endangered in some regions of Germany, Austria and Switzerland — check local conservation regulations before harvesting and only use non-threatened stands.
- Storage:
- 24 months — Store dried root pieces airtight in tins or dark glass jars, cool and dry. Shelf life up to 2 years. Quality indicator: characteristic slightly sweet smell; grey-brown outer bark, yellowish-white inner tissue. Discard if musty smell or mould is detected.
- Time of day:
- Harvest flowering aerial parts (stems, leaves, flowers) from June to August, preferably on dry mornings (10–12), once dew has evaporated. Cut the flower heads with the top 15–20 cm of stem. Avoid hard, lignified stem sections.
- Drying:
- Loosely tie plant parts into small bundles (flowers downward), hang in a shaded, well-ventilated spot or spread in a single layer on cloth. Temperature max. 35 °C. Drying time 5–10 days. Dry when leaves rustle when rubbed and stems break easily. Less commonly used in folk medicine than the root — Kommission E and EMA refer only to the root (Ononidis radix). Aerial parts are recorded in folk medicine for herbal teas (blends, cosmetic preparations).
- Storage:
- 12 months — Dry, cool, light-protected in glass jars or tins. Use within 1 year.
- Isoflavone (Formononetin, Ononin, Onogenin, Biochanin A)FlavonoidContent: 0.1-0.3 %Root
Characteristic lead compound group of restharrow. Formononetin is the dominant isoflavone; ononin is its 7-O-glucoside. Isoflavones act as weak phytoestrogens and are associated with the traditional use for urinary complaints and the historical folk use for menopausal symptoms. Biochemically active as phytoestrogens via oestrogen receptors.
- Ononidin (Onocerin-Glucosid)GlycosideContent: 0.1-0.2 %Root
Triterpene glycoside (glycoside of onoserin/onocerin), attributed with anti-inflammatory and weakly aquaretic properties. Partially responsible for the diuretic effect described in folk medicine. Animal experimental data indicate uterine-stimulating potential — basis for the pregnancy contraindication.
- Triterpensaponine (Onocerin, beta-Sitosterol-Glucosid)SaponinContent: 0.3-1.0 %Root
Pentacyclic triterpenes (onocerin as the lead substance) and steroidal saponins. Contribute to the anti-inflammatory and possibly aquaretic overall effect. Onocerin is structurally unusual — a tetracyclic triterpenoid with 2 hydroxyl groups.
- Ätherisches Öl (Carvon, Anethol, Menthol-Derivate — Spuren)Essential oilContent: 0.02-0.1 %Aerial parts
Only traces in the root; slightly more in aerial parts and flowers. The fresh plant has a characteristic slightly resinous to spicy scent. Pharmacologically not relevant at therapeutic root dosages.
- Flavonoide (Kaempferol, Quercetin-Glykoside, Liquiritigenin)FlavonoidContent: 0.2-0.5 %Aerial parts
Flavonols and flavanones in leaves and flowers. Kaempferol and quercetin act as antioxidants and mild anti-inflammatories. Liquiritigenin (a flavanone related to liquorice) is structurally related to the isoflavones and contributes to the weak phytooestrogenic activity.
- Phenolcarbonsäuren (Kaffeesäure, p-Cumarsäure, Chlorogensäure)Phenolic acidContent: 0.1-0.3 %Root
Widespread in Fabaceae. Antioxidant, mildly anti-inflammatory; complement the overall effect of the root extract. Chlorogenic acid is also known from coffee beans and has documented antioxidant activity.
- Gerbstoffe / kondensierte TannineTanninContent: 2.0-5.0 %Root
Relatively high tannin content in the root (condensed catechin tannins). Astringent on urinary mucosa; may partly explain soothing effect in cystitis. In sensitive individuals the high tannin content may cause nausea — tea best not taken on an empty stomach.
- Stärke und Zucker (Saccharose, Glucose — in der Wurzel)PolysaccharideContent: 10-20 %Root
Restharrow roots contain notable amounts of starch and sugars. Historically the root could be used as a food in lean times (roasted as a coffee substitute). No independent pharmacological contribution to medicinal effect.
- [1]MonographKommission E — Ononidis radix (Hauhechelwurzel), Monographie (positiv), BAnz Nr. 50, 1989; überprüft 1990(accessed: 2026-05-21)
- [2]MonographEMA/HMPC — European Union herbal monograph on Ononis spinosa L., radix (Draft / Final, EMA/HMPC/437229/2010)(accessed: 2026-05-21)
- [3]MonographESCOP Monographs — Ononidis Radix (Restharrow Root), 2nd edition supplement 2009(accessed: 2026-05-21)
- [6]MonographPlants For A Future (PFAF) — Ononis spinosa database entry(accessed: 2026-05-21)
- [4]BookWichtl, Max (Hrsg.) — Teedrogen und Phytopharmaka, 5. Auflage. Hauhechelwurzel — Ononidis radix. Wissenschaftliche Verlagsgesellschaft, Stuttgart 2009. ISBN 978-3-8047-1917-0.(accessed: 2026-05-21)
- [5]BookMadaus, Gerhard — Lehrbuch der biologischen Heilmittel, Band II: Ononis spinosa (Hauhechel), 1938 (Public Domain)(accessed: 2026-05-21)
- [7]WikipediaDornige Hauhechel (Wikipedia DE)(accessed: 2026-05-21)