© Brandt, Wilhelm; Gürke, M.; Köhler, F. E.; Pabst, G.; Schellenberg, G.; Vogtherr, Max. · Public domain · Commons
Juglans regia
CautionEchte Walnuss · (Juglans regia)
Walnut family (Juglandaceae)
Description
The familiar kernels of the common walnut ripen in autumn, but medicinally it is the leaves, gathered in summer, that matter most from this walnut-family tree. An infusion or bath additive made from dried walnut leaves carries a positive Kommission E assessment for mild superficial skin inflammation and excessive perspiration, credited mainly to ellagitannins and tannins. Compresses have traditionally been used for minor wounds and insect bites, while a tincture from the green, still-unripe husks was used folk-medicinally on skin fungus — the juglone they contain temporarily stains skin brown. As food, the nuts themselves are particularly valuable: their high alpha-linolenic acid content is linked by EFSA to a supportive effect on blood lipid levels. Internal use of leaf tea should be kept short, no more than two to three weeks, due to the juglone content. Walnuts are also among the most common triggers of severe nut allergy, and fresh green husks can cause contact dermatitis in sensitive skin.
External bath infusion from dried walnut leaves — Kommission E positive monograph for mild superficial skin inflammation and excessive perspiration. Key actives: ellagitannins and tannins.
Preparation & dosage
BATH ADDITIVE (Kommission E positive, external): Pour 1 litre of boiling water over 25–50 g of dried walnut leaves (Folia Juglandis), steep covered 15 min, strain and add to full bath (~37–38 °C, 200–250 litres) or partial bath. Soak 15–20 min. Indications per Kommission E: mild superficial skin inflammation and excessive sweating (hyperhidrosis) of hands and feet. Use daily or every second day; not on open wounds, infected lesions, or extensive skin conditions without medical assessment. High tannin content (ellagitannins, gallotannins) provides astringent and antimicrobial action.
- Dry amount
- 25–50 g
- Doses per day
- 1×
- Max duration
- 4 weeks
Traditional walnut-leaf compress for minor wound care, insect bites and small-area eczema — astringent and mildly antiseptic tannin action.
Preparation & dosage
COMPRESS: Pour 500 ml boiling water over 10–20 g dried walnut leaves, steep 15 min, strain, cool to body temperature. Dip sterile compress or clean linen cloth, wring lightly, place on affected skin. Leave 10–15 min, repeat twice daily. Traditional use for minor wound care (abrasions, insect bites), mildly inflamed skin and small-area eczema. Do not apply to deep, purulent or infected-appearing wounds.
- Dry amount
- 10–20 g
- Doses per day
- 2×
- Max duration
- 3 weeks
Traditional infusion of dried walnut leaves for mild digestive complaints — short-term only, as juglone content is concerning with long-term use.
Preparation & dosage
INTERNAL INFUSION (traditional, short-term): 1.5–3 g dried, chopped walnut leaves in 250 ml boiling water, covered, steep 10 min, strain. Max 2 cups daily, not longer than 3 weeks without medical consultation. Traditional use for mild digestive complaints (bloating, mild diarrhoea) and as adjunct internal treatment for skin purification. IMPORTANT: juglone content higher in fresh leaves — use only dried drug (Folia Juglandis). Avoid long-term internal use due to juglone. Discontinue at first signs of nausea or gastric discomfort.
- Dry amount
- 1.5–3 g
- Doses per day
- 2×
- Max duration
- 3 weeks
Folk tincture from green walnut husks — external use for skin fungi, warts and excessive sweating; juglone stains skin brown (temporary).
Preparation & dosage
GREEN WALNUT HUSK TINCTURE (folk, external): Immature green walnut husks (Pericarpium Juglandis viride, harvested July–August) macerated in 40–60 % ethanol (DER 1:5), steep in dark 4 weeks, filter. Apply diluted (~1:10 in water) to affected skin, twice daily. Folk use for skin fungal infections (ringworm, tinea pedis), warts and excessive sweating. Caution: juglone stains skin dark brown (temporary) — avoid contact with clothing and nails or wear gloves. Do not apply on mucous membranes or large areas.
- Liquid amount
- 2–5 ml
- Doses per day
- 2×
- Max duration
- 4 weeks
Walnut as food — EFSA-recognised effect on blood lipid levels (ALA/omega-3); clinical evidence for LDL reduction, endothelial function and antioxidant status.
Preparation & dosage
WALNUT AS FOOD (evidence-based nutrition): 30–42 g (approx. one handful, ~7–10 halves) daily, raw or lightly roasted, unsalted, unsweetened. Prefer morning or between meals. EFSA approved health claims for walnuts regarding alpha-linolenic acid (ALA, omega-3) and maintenance of normal blood cholesterol levels (EU Regulation 432/2012). Clinical trials show contribution to normal LDL-cholesterol levels (~5–15 % reduction), vascular endothelial function and antioxidant status. Contains melatonin (sleep-promoting effect of evening intake discussed). Total fat content very high (~65 g/100 g) — consider caloric density.
- Dry amount
- 28–42 g
- Doses per day
- 1×
Folk bitter tea from walnut leaves for sluggish digestion and biliary complaints — strictly short-term due to juglone content.
Preparation & dosage
FOLK BITTER TEA (short-term): 1–2 tsp dried walnut leaves in 200 ml boiling water, steep 8 min, strain. 1 cup daily (preferably before meals). Folk tradition for sluggish digestion, biliary complaints and as 'blood purifier'. Bitter-astringent action from juglone, tannins and bitter principles. Strictly limit use to 2 weeks max; then at least 4 weeks break. Not for internal use in children under 12.
- Dry amount
- 1–2 g
- Doses per day
- 1×
- Max duration
- 2 weeks
Walnuts and cold-pressed walnut oil as food — high ALA/omega-3 and vitamin E content; nut liqueur (Nocino) from green walnuts as traditional folk specialty.
Preparation & dosage
KITCHEN AND WALNUT OIL: Fully ripe dried walnuts are versatile — raw as snack, chopped in bread, salads, pesto, muesli and desserts. Cold-pressed walnut oil (rich in ALA/omega-3 and vitamin E) as salad oil or finishing drizzle (not suitable for high-heat cooking, smoke point ~160 °C). Store walnut oil cool and dark — highly oxidation-sensitive due to high PUFA content, use within 2–3 months. Store dried nuts cool (< 15 °C) in closed containers; up to 1 year under optimal conditions. Unripe green walnuts traditionally made into nut liqueur (Nocino/Walnussgeist): macerated in 40–50 % alcohol with spices for 6–8 weeks.
WALNUT LEAVES (Folia Juglandis): External — considered safe for short-term use per Kommission E. Internal — restrict to short-term use (max 2–3 weeks) due to juglone content (phenolic naphthoquinone); long-term use may be hepatotoxic and irritate mucous membranes. NUT ALLERGY: Walnuts are among the most common triggers of severe IgE-mediated food allergies (EU labelling mandatory — 'Contains tree nuts'). Avoid all walnut preparations with known tree nut allergy. Green walnut husks and leaves: juglone is phytotoxic and can cause contact dermatitis — avoid skin contact in sensitive individuals; wear disposable gloves when harvesting. KERNEL OIL: High PUFA content means rapid rancidity — rancid oil contains lipid peroxides that may increase oxidative stress; do not use rancid oil. About the genus: The ASPCA lists black walnut (Juglans nigra) as toxic to dogs. The English walnut is not classified there. Veterinary practice regards mouldy fallen nuts as the main hazard — they can contain tremorgenic mycotoxins.
Walnut kernels as food in usual amounts are considered safe. Walnut leaf preparations (tea, tincture) in therapeutic doses should be avoided in pregnancy due to lack of safety data — juglone has shown mutagenic properties in animal studies. External baths with walnut leaves: no reliable data; short-term use probably low-risk but caution advised.
Walnut kernels as food: safe. Therapeutic walnut leaf preparations (internal) should be avoided during lactation due to juglone — possible transfer to infant. External use (bath, compress) on intact skin and limited area is probably safe.
Walnuts as food: whole nuts or coarse pieces — avoid for children under 4 due to choking hazard; ground or as paste generally possible from weaning (monitor for allergy). Internal walnut leaf preparations not recommended for children under 12 — no safety data, juglone risk. External use (bath) in school-age children with skin problems traditionally common; monitor tolerance carefully.
Drug interactions
Antikoagulantien / Cumarine (Warfarin, Phenprocoumon)
Walnut kernels contain notable vitamin K (~2.7 µg/100 g) — not relevant at usual dietary amounts. Very high regular walnut consumption (> 100 g daily) could affect INR in vitamin-K-sensitive patients. Additionally, walnut polyphenols (ellagitannins) inhibit CYP2C9 in vitro — theoretical inhibition of warfarin metabolism. INR monitoring recommended with major sudden changes in walnut intake.
Schilddrüsenmedikamente (Levothyroxin, Thyroxin)
Walnuts contain tannins and dietary fibre that can reduce levothyroxine absorption in the small intestine. Do not take walnuts simultaneously with thyroid hormones — maintain at least 4 hours separation.
Eisenpräparate und andere Mineralstoff-Supplemente
Tannins (ellagitannins, gallotannins) in walnut leaves and kernels can reduce absorption of iron, zinc and other divalent cations by complexation. Do not take iron supplements and walnut leaf tea simultaneously — 2 hours separation.
Contraindications
- Known hypersensitivity or allergy to walnuts or other tree nuts (tree nut allergy — IgE-mediated, anaphylaxis risk).
- Internal use of walnut leaf preparations in known liver disease (juglone hepatotoxicity).
- Internal use of walnut leaf preparations for more than 3 weeks without medical supervision.
- Pregnancy and lactation (internal therapeutic walnut leaf doses — avoid due to lack of data and juglone).
Harvested part: leaves (summer), ripe nuts (autumn)
- Time of day:
- Dry, sunny morning (9–12), once morning dew has fully evaporated. Juglone content is highest in fresh leaves — wear disposable or protective gloves as juglone stains hands brown.
- Drying:
- Harvest young, fully expanded leaves from the middle third of the crown — no diseased, damaged or gall-infested leaves. Spread singly (do not pile) on screens or paper and dry in shade at room temperature (max. 40 °C) — heat or direct sun destroys tannins and increases juglone decomposition. Drying time: 5–10 days depending on humidity until leaves crackle. Store dried drug (Folia Juglandis) in paper bags or linen sacks, airy and dark, max. 1 year. Protect from humid air — tannins hydrolyse and potency decreases.
- Storage:
- 12 months — In paper bags or linen sacks, airy, dark and dry (< 12 % residual moisture). Not in plastic bags — condensation promotes mould and tannin hydrolysis. Use within 1 year.
- Time of day:
- Dry autumn day (September–October) after natural drop or light shaking of the tree. Harvest nuts with green outer husk (for walnut spirit/Nocino: July, unripe) or fully ripe with splitting brown husk. Process green husks only with disposable gloves — juglone staining is permanent.
- Drying:
- Ripe nuts: remove green outer husk (gloves!), wash, spread in thin layer in airy, cool location (barn, covered outdoor area, no direct frost) to dry 2–4 weeks until shell sounds completely dry when shaken (rattling = still too moist). Then store in nets or wooden crates, cool and dry. Unripe nuts (July): process immediately into tincture or walnut spirit — do not dry.
- Storage:
- 12 months — In shell: cool (< 15 °C), airy, dark — up to 12 months. Shelled, unrefrigerated: quickly rancid (max. 4 weeks at room temperature). Shelled, refrigerated: 3–6 months. Frozen: up to 12 months (minimal quality loss). Walnut oil: dark, cool, tightly closed — 2–3 months after opening.
- Juglon (5-Hydroxy-1,4-naphthochinon)OtherContent: 0.1-1 %Leaf
Characteristic lead compound of the genus Juglans. Phenolic naphthoquinone with antibacterial, antifungal and antiparasitic activity — contributes to folk-documented action against skin fungi. Cytotoxic and hepatotoxic in high doses; phytotoxic to many plant species (allelopathy). Higher concentration in fresh leaves and green husks than in dried drug. Responsible for brown skin staining on contact.
- Ellagitannine (Tellimagrandin I und II, Juglanin, Casuarinin)TanninContent: 2-4 %Leaf
Hydrolysable tannins as quantitatively dominant constituents of the leaves. Strongly astringent, antimicrobial and anti-inflammatory — primary actives behind the Kommission E-recognised external use for skin inflammation and hyperhidrosis. Hydrolysable in the gut to ellagic acid and gallic acid.
- Alpha-Linolensäure (ALA, C18:3 omega-3)OtherContent: 8-14 % (im Kernöl: ca. 13 % der Fettsäuren)Seed
Plant-based omega-3 fatty acid — walnuts are one of the richest plant sources of ALA. EFSA health claim approved: 'ALA contributes to the maintenance of normal blood cholesterol levels' (at 2 g ALA daily intake, equivalent to ~7–10 walnut halves). Precursor to long-chain omega-3 fatty acids EPA and DHA (human conversion rate limited: ~5–15 % to EPA, < 1 % to DHA).
- Linolsäure (LA, C18:2 omega-6)OtherContent: 38-48 % (Hauptfettsäure im Kernöl)Seed
Essential omega-6 fatty acid as main fatty acid of walnut oil. Combined with ALA, yields a favourable omega-6:omega-3 ratio (~4:1) — better than most other vegetable oils. Contributes to normal blood lipid levels and cell membrane integrity.
- Flavonoide (Quercetin, Kämpferol, Myricetin, Naringenin)FlavonoidContent: 0.1-0.5 %Leaf
Flavonols and flavanones in the leaves; quercetin and kaempferol as main representatives. Antioxidant, anti-inflammatory; complement the astringent tannin action. In the kernels mainly as pedunculagin and glansrin (ellagitannin derivatives).
- Vitamin E (alpha-Tocopherol)VitaminContent: 0.7-2 mg/100 g Frischgewicht KernSeed
Fat-soluble antioxidant — protects polyunsaturated fatty acids in walnut oil from oxidation. Daily intake of 30 g walnuts covers approx. 5–10 % of daily requirement. Higher concentration in cold-pressed walnut oil (~20 mg/100 ml).
- MelatoninOtherContent: 3.5-4.5 ng/g Frischgewicht KernSeed
Neurohormone also found in plant tissues. Walnuts are among the melatonin-richest foods; human studies have shown walnut consumption increases blood ORAC capacity and serum melatonin levels. Possible influence on circadian rhythm with evening consumption — clinical significance not yet conclusively established.
- Phenolcarbonsäuren (Ellagsäure, Gallussäure, Chlorogensäure)Phenolic acidContent: 0.2-0.8 %Leaf
Hydrolysis products of ellagitannins plus free phenolic acids. Ellagic acid is released in the gut from ellagitannins and further metabolised to urolithins (by gut bacteria) — urolithin A shows antioxidant and moderately anti-inflammatory properties in studies. Gallic acid: antimicrobial and antioxidant.
- [1]MonographKommission E — Juglandis folium (Walnussblätter), Monographie (positiv), BAnz Nr. 43, 02.03.1989(accessed: 2026-05-21)
- [2]MonographEMA/HMPC — Community herbal monograph on Juglans regia L., folium (EMA/HMPC/289430/2009, Final 2010)(accessed: 2026-05-21)
- [3]MonographESCOP Monographs — Juglandis Folium (Walnut Leaf), 2nd edition supplement(accessed: 2026-05-21)
- [6]MonographPlants For A Future (PFAF) — Juglans regia database entry(accessed: 2026-05-21)
- [7]MonographEFSA Panel on Dietetic Products — Scientific Opinion on the substantiation of health claims related to walnuts and maintenance of normal blood LDL-cholesterol concentrations (ID 1156, 1158) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal 2011;9(4):2074.(accessed: 2026-05-21)
- [8]MonographRos, Emilio — Health Benefits of Nut Consumption. Nutrients 2010, 2(7), 652–682. (WHO-listed evidence review)(accessed: 2026-05-21)
- [11]MonographCliniTox Giftpflanzen — Juglans regia L.: schwach giftig (+) (Institut für Veterinärpharmakologie und -toxikologie, Universität Zürich)(accessed: 2026-08-10)
- [4]BookWichtl, Max (Hrsg.) — Teedrogen und Phytopharmaka, 5. Auflage. Wissenschaftliche Verlagsgesellschaft Stuttgart, 2009. Artikel: Juglandis folium.(accessed: 2026-05-21)
- [5]BookMadaus, Gerhard — Lehrbuch der biologischen Heilmittel, Band II: Juglans regia (Walnuss), 1938 (Public Domain)(accessed: 2026-05-21)
- [9]WikipediaEchte Walnuss (Wikipedia DE)(accessed: 2026-05-21)
- [10]WikipediaJuglans regia (Wikipedia EN)(accessed: 2026-05-21)