© Walther Otto Müller, in Köhler's Medizinal-Pflanzen (1887), Plate 120 · Public domain · Commons
Alder buckthorn
Caution🐾Faulbaum · (Frangula alnus)
Buckthorn family (Rhamnaceae)
Description
Alder buckthorn (Frangula alnus, syn. Rhamnus frangula) is a thornless, deciduous shrub of 2 to 6 metres in the buckthorn family, with dark bark and a striking lemon-yellow inner bark. The medicinal part is the dried bark of stems and branches, known as frangula bark (Frangulae cortex). It contains anthraquinone glycosides (glucofrangulin A and B, frangulin A and B) and acts as a mild stimulant laxative on the large intestine. The bark must be stored for at least one year or heat-treated before use, because fresh bark causes violent vomiting.
CONTRAINDICATED during pregnancy
Do not use during pregnancy; stimulant anthraquinone laxatives are not recommended in pregnancy.
CONTRAINDICATED during breastfeeding
Do not use while breastfeeding, as metabolites may pass into breast milk.
CONTRAINDICATED for children
Do not use in children under 12 years of age.
Critical drug interactions with:
Herzglykoside (z. B. Digoxin)
Short-term occasional constipation
Preparation & dosage
Pour 150 ml of hot water over 0.5 to 2.5 g of dried frangula bark aged at least one year, steep 10 to 15 minutes, then strain. Take once daily, preferably in the evening. The dose is standardised to 10 to 30 mg hydroxyanthracene derivatives (calculated as glucofrangulin A) per day; always use the lowest effective dose. Do not use for longer than one week without medical advice.
- Dry amount
- 0.5–2.5 g
- Doses per day
- 1×
- Max duration
- 1 weeks
⚠ Age restriction: ≥ 12 years — Only for adults and adolescents over 12 years of age.
Standardised extract for constipation
Preparation & dosage
Liquid or standardised dry-extract preparations of frangula bark are dosed to deliver 10 to 30 mg hydroxyanthracene derivatives (as glucofrangulin A) per day. Take once daily in the evening, always at the lowest individually effective dose. Short-term only, maximum one week. Standardised commercial products are more reliably dosed than home-made tinctures.
- Doses per day
- 1×
- Max duration
- 1 weeks
⚠ Age restriction: ≥ 12 years — Only for adults and adolescents over 12 years of age.
Traditional digestive stimulation
Preparation & dosage
Traditionally, a weak infusion of the aged bark was used as a gentle means of stimulating bowel activity and digestion. Steep 0.5 to 2 g of stored bark in 150 ml of hot water for 10 minutes. This use is traditional and not supported by clinical trials; the same safety limits as for the laxative use apply.
- Dry amount
- 0.5–2 g
- Doses per day
- 1×
- Max duration
- 1 weeks
⚠ Age restriction: ≥ 12 years — Only for adults and adolescents over 12 years of age.
Frangula bark is an anthraquinone-containing stimulant laxative and should be used only short term (maximum one week) and not continuously without medical advice. Fresh bark is toxic and causes violent vomiting, nausea and colicky abdominal pain; only bark aged at least one year or heat-treated at 80 to 100 °C may be used. The berries and leaves are also toxic. Do not use during pregnancy, breastfeeding or in children under 12 years. Prolonged or excessive use can cause electrolyte losses, especially loss of potassium, habituation, worsening of constipation (atonic colon) and harmless discolouration of the urine. Seek medical advice if symptoms persist.
Do not use during pregnancy; stimulant anthraquinone laxatives are not recommended in pregnancy.
Do not use while breastfeeding, as metabolites may pass into breast milk.
Do not use in children under 12 years of age.
Drug interactions
Herzglykoside (z. B. Digoxin)
Potassium loss from prolonged use can increase the action and toxicity of cardiac glycosides.
Diuretika
Concurrent use can intensify potassium loss and aggravate electrolyte imbalance.
Kortikosteroide
Increased potassium loss when used together with adrenocortical steroids.
Antiarrhythmika
Electrolyte imbalance from potassium loss may affect the action of antiarrhythmic medicines.
Contraindications
- Intestinal obstruction (ileus) and narrowing of the intestine
- Intestinal atony (loss of intestinal muscle strength)
- Appendicitis
- Inflammatory bowel disease (Crohn's disease, ulcerative colitis)
- Abdominal pain of unknown origin
- Severe dehydration with water and salt loss
- Children under 12 years of age
- Pregnancy and breastfeeding
Harvested part: Bark of stems and branches
- Time of day:
- In spring to early summer, when the bark peels easily from the wood (sap flow).
- Drying:
- Peel the bark from stems and branches and dry it in air or sun. Before medicinal use, store for at least one year or heat at 80 to 100 °C so that the fresh, emetic anthranols are oxidised.
- Storage:
- 24 months — Dry, protected from light and moisture; use no earlier than after one year of ageing.
- Glucofrangulin AGlycosideContent: min. 7%Bark
Anthraquinone glycoside and the pharmacopoeial marker substance; the bark must contain at least 7% glucofrangulins (calculated as glucofrangulin A).
- Glucofrangulin BGlycosideBark
Anthraquinone glycoside that together with glucofrangulin A produces the laxative effect.
- Frangulin AGlycosideBark
Anthraquinone glycoside (emodin rhamnoside), formed during ageing from the glucofrangulins.
- Frangulin BGlycosideBark
Anthraquinone glycoside of frangula bark, contributing to the laxative effect.
- EmodinGlycosideBark
Anthraquinone aglycone; fresh bark contains reactive precursors that cause vomiting and are oxidised during ageing or heating.
- Gerbstoffe (Tannine)TanninBark
Astringent accompanying substances of the bark.
- FlavonoideFlavonoidBark
Secondary plant compounds present in smaller amounts.
- [1]MonographEuropean Union herbal monograph on Rhamnus frangula L. (Frangula alnus Miller), cortex (Revision 1)(accessed: 2026-06-12)
- [2]MonographFrangula bark summary for the public (HMPC) - European Medicines Agency(accessed: 2026-06-12)
- [3]MonographAssessment report on Rhamnus frangula L., cortex (Revision 1) - European Medicines Agency(accessed: 2026-06-12)
- [8]MonographCliniTox Giftpflanzen — Frangula alnus Mill.: stark giftig ++ (Institut für Veterinärpharmakologie und -toxikologie, Universität Zürich)(accessed: 2026-08-10)
- [4]WikipediaFaulbaum - Wikipedia (deutsch)(accessed: 2026-06-12)
- [5]WikipediaFrangula alnus - Wikipedia(accessed: 2026-06-12)
- [7]CommonsFile:Rhamnus frangula - Köhler's Medizinal-Pflanzen-120.jpg - Wikimedia Commons(accessed: 2026-06-12)
- [6]WikidataFrangula alnus (Q161139) - Wikidata(accessed: 2026-06-12)
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