© Otto Wilhelm Thomé, Flora von Deutschland (1885) · Public domain · Commons
Arnica
CautionArnika · (Arnica montana)
Daisy family (Asteraceae)
Description
Arnica is a perennial mountain plant with brilliant yellow-orange ray flowers that grows on nutrient-poor meadows in low mountain ranges and the Alps. It is protected by nature conservation law in Germany and must not be collected in the wild. Its flower extracts are one of the best-known traditional remedies for bruises and contusions — exclusively for external use.
External use only!
This plant must NOT be taken internally. Use only as compress, salve, or bath.
CONTRAINDICATED during pregnancy
Arnica montana must not be used during pregnancy. Helenalin and related sesquiterpene lactones may have uterotonic activity. Per the EMA monograph, sufficient safety data are lacking; given the known toxicity of constituents, all external use during pregnancy should be avoided.
CONTRAINDICATED during breastfeeding
No adequate safety data in lactation. Due to the toxicity of helenalin and potential transfer into breast milk, use during lactation is not recommended. The EMA monograph excludes breastfeeding from the indicated population.
Arnica tincture (1:10 in 70 % ethanol), diluted 1:3 to 1:10 with water, applied as a moist compress to bruises, contusions, sprains and blunt injuries. External use on intact, unbroken skin only. Apply compress 2-3 times daily for 20-30 minutes, covered with a cloth. Kommission E positively assessed arnica for blunt injuries, haematomas, and muscle and joint complaints.
Undiluted or lightly diluted arnica tincture (DAB: Tinctura Arnicae 1:10, ethanol 70 %) rubbed in for muscle soreness, strains and joint pain after physical exertion. Apply to intact skin only; do not cover with occlusive dressings. German Commission E positively assessed arnica for topical use on blunt trauma; the EMA classifies the use as traditional.
Arnica ointment or gel (standardised on sesquiterpene lactones, typically 0.5-1 % helenalin derivatives or equivalent to 15 % tincture in ointment base) for external use on blunt injuries, muscle pain, joint complaints, bruises and sprains. Apply thinly 2-3 times daily; do not use on open wounds. German Commission E positively assessed arnica preparations for external use; the EMA monograph lists arnica as traditional use.
Arnica sitz bath or partial/foot bath for tired, aching muscles and mild joint complaints after physical work: 2-3 tbsp dried arnica flowers (approx. 5-10 g) infused in 1 litre boiling water, steeped 10 minutes, strained and added to bath water (temperature 36-38 °C, bathing time 15-20 minutes). Traditional folk application, well documented in German-language herbal literature (Wichtl, Hänsel/Sticher). Do not use on damaged skin, open wounds, or in known Asteraceae allergy.
Arnica tincture diluted with water (1:5 to 1:10), applied as a compress for insect bites and superficial skin irritations (not on open wounds). Apply compress with a clean cloth to the affected area, leave for 15-20 minutes. Kommission E explicitly lists insect bites as an indication for external arnica preparations. Only on intact skin — use on open wounds is contraindicated (local mucosal irritation, contact dermatitis risk).
Standardised arnica gel (50 g arnica flower tincture per 100 g, equivalent to ~15 % mother tincture) clinically studied for osteoarthritis of finger joints and knee: In randomised controlled trials (e.g. Knuesel et al. 2002, Wiesenauer 2004), arnica gel showed comparable efficacy to ibuprofen gel in pain reduction and improvement of joint function. Apply 3 times daily to affected joints for at least 3-6 weeks to assess benefit. Use only as adjunct, not as replacement for physician-prescribed osteoarthritis therapy.
Folk medicine application of arnica tincture (heavily diluted 1:10 in water) for chilblains (perniones) and cold-induced skin damage: as compress or gentle rub to promote local circulation. Long-standing tradition in German folk medicine (Kneipp tradition) and Swiss herbal medicine (Künzle). Clinical evidence lacking — purely traditional use. Only on intact, unbroken skin.
⚠ External use only
CRITICAL — EXTERNAL USE ONLY: Arnica montana must NEVER be taken internally. Even small oral doses of the herbal drug can cause severe poisoning through the sesquiterpene lactone helenalin: mucosal irritation, gastroenteritis, cardiac arrhythmia (cardiotoxicity), CNS disturbances and respiratory paralysis. External use: do NOT apply to open wounds, abrasions or damaged skin — risk of local irritation and systemic absorption of helenalin. ASTERACEAE ALLERGY (Compositae family) is an absolute contraindication. Arnica can cause severe allergic contact dermatitis. Conservation status: Arnica montana is strictly protected in Germany, Austria and Switzerland — wild collection is prohibited. Use only pharmacy-grade products or cultivated material. Homeopathic arnica preparations (dilutions D4 and above) are governed by different rules from the phytotherapeutic drug — only phytotherapeutic preparations are described here.
Arnica montana must not be used during pregnancy. Helenalin and related sesquiterpene lactones may have uterotonic activity. Per the EMA monograph, sufficient safety data are lacking; given the known toxicity of constituents, all external use during pregnancy should be avoided.
No adequate safety data in lactation. Due to the toxicity of helenalin and potential transfer into breast milk, use during lactation is not recommended. The EMA monograph excludes breastfeeding from the indicated population.
Per the EMA monograph, not recommended for children under 12 years (insufficient safety data). In children over 12 years, use only under medical supervision and for a clear indication. Allergy risk particularly important. Do not apply to the face or large body surface areas.
Drug interactions
Antikoagulanzien / Thrombozytenaggregationshemmer (Warfarin, Phenprocoumon, ASS, Clopidogrel)
Helenalin inhibits platelet aggregation in vitro and may additively enhance the anticoagulant or antiplatelet effect of blood thinners. Systemic absorption from small-area topical use is low; with large-area application or occlusion, clinically relevant interaction is possible. Monitor bleeding time.
Blutdrucksenkende Mittel (Antihypertensiva)
Arnica extracts at higher systemic concentrations may exert blood pressure effects. Clinically not relevant with intended external use on intact skin; with large-area or damaged skin application, theoretical additive hypotension is possible.
Lokalanästhetika (Benzocain, Lidocain — topische Präparate)
Combined use of topical arnica with other local anaesthetics or skin-irritating substances on the same site may cumulate irritation and increase contact dermatitis risk. Do not apply simultaneously to the same skin area.
Contraindications
- Hypersensitivity to arnica or other Asteraceae/Compositae, especially to sesquiterpene lactones (cross-reactivity with chamomile, calendula, chrysanthemum, yarrow).
- Application to open wounds, abrasions, eczema, inflamed or irritated skin — increased absorption of helenalin and risk of sensitisation.
- Internal ingestion of any arnica phytotherapeutic preparation — absolutely contraindicated due to the cardiotoxicity and mucosal toxicity of helenalin.
- Pregnancy and lactation.
- Children under 12 years (EMA monograph).
Harvested part: flowers (in Germany only from cultivation or pharmacies!)
- Time of day:
- On a dry, sunny morning (9–12), once dew has dried off. Sesquiterpene lactone and flavonoid content is highest in fully open flowers in midday sun.
- Drying:
- WARNING — CONSERVATION LAW: Arnica montana is strictly protected in Germany, Austria and Switzerland. Wild collection is PROHIBITED. Use only flowers from certified cultivation (e.g. Balkan or Sauerland crops) or pharmacy-grade material. Harvest from cultivated stands: pick fully open capitula (flower heads without stalk) shortly after ray florets open, before pollen is shed. Dry in a single layer on cloth at 35-40 °C in shade or dehydrator (no direct sunlight — UV degrades sesquiterpene lactones). Full drying takes 2-4 days. Arnica flowers smell intensely aromatic when drying and may irritate mucous membranes in sensitive persons — ensure good ventilation; wear respiratory protection if prone to allergy.
- Storage:
- 12 months — Protected from light in well-sealed glass containers or tins, dry, cool (max. 25 °C), moisture-proof. Use within 12 months — sesquiterpene lactone content drops sharply after. Discard immediately if browning, musty smell or mould.
- Time of day:
- Rhizome digging in autumn after aerial parts have withered (September–October). Time of day less critical than for flowers — cool morning hours preferred.
- Drying:
- WARNING — CONSERVATION LAW: Arnica montana rhizomes may also only be harvested from legal cultivation, never from wild stands. In phytotherapy, the root (Arnicae radix) is used far less commonly than the flowers (Arnicae flos) — sesquiterpene lactone content is similar but flavonoid concentration is lower. After digging, clean roots, remove soil, cut into slices and dry at 35-45 °C in a dehydrator (8-12 hours depending on thickness). Fully dried pieces are woody-hard and snap cleanly.
- Storage:
- 24 months — Light-protected, dry, cool in glass containers or linen bags. Storage life up to 2 years with correct conditions.
- Sesquiterpenlactone: Helenalin und Dihydrohelenalin (sowie deren Ester)SesquiterpeneContent: 0.2-0.8 %Flower
Pharmacological lead compounds of arnica flowers. Helenalin and its esters (helenalin acetate, helenalin methacrylate) are responsible for the anti-inflammatory and analgesic effects in external use (inhibition of NF-κB and prostaglandin synthesis). Simultaneously the main cause of toxicity on internal ingestion (cardiotoxicity, mucosal irritation) and the sensitisation potential (contact dermatitis, cross-reactive with other sesquiterpene lactone-containing Asteraceae).
- Flavonoide: Isoquercitrin, Luteolin-7-glucosid, Astragalin, QuercetinFlavonoidContent: 0.4-0.6 %Flower
Flavonoid fraction of arnica flowers. Isoquercitrin (quercetin-3-glucoside) and luteolin-7-glucoside are quantitatively dominant. Antioxidant and mildly capillary-protective; contribute to overall activity in bruises and haematomas. Pharmacologically synergistic with sesquiterpene lactones.
- Ätherisches Öl (Thymol, Thymolderivate, Sesquiterpene)Essential oilContent: 0.2-1.0 %Flower
The essential oil of arnica flowers contains thymol and thymol derivatives as well as various sesquiterpenes. Responsible for the characteristic aromatic odour of the drug. Antimicrobial and mildly circulation-promoting; contributes to the overall topical activity profile.
- Phenolcarbonsäuren: Chlorogensäure, Kaffee-säure, 3,5-DicaffeoylchinasäurePhenolic acidContent: 0.5-1.5 %Flower
Caffeoylquinic acid esters, particularly chlorogenic acid and cynarin-type compounds. Antioxidant and anti-inflammatory; lipoxygenase-inhibiting. Contribution to the anti-inflammatory activity of arnica flowers in topical application.
- Carotinoide: Beta-Carotin, Lutein, ZeaxanthinOtherContent: 0.02-0.1 %Flower
Carotenoids are partly responsible for the brilliant yellow-orange colouration of arnica flowers. Antioxidant properties; pharmacologically of secondary importance in external use compared to sesquiterpene lactones and flavonoids.
- Polysaccharide (Inulin, Fructooligosaccharide)PolysaccharideContent: 1-4 %Flower
Mucilaginous polysaccharides of arnica flowers with emollient character; support even distribution and adhesion of ointment bases on skin. Phytotherapeutically of minor importance in the drug, but technologically relevant for formulation.
- Triterpene: Arnidiol, Faradiol und deren FettsäureesterOtherContent: 0.4-1.5 %Flower
Faradiol monoesters (faradiol palmitate, faradiol myristate) are concentrated in the resin glands of arnica flowers and contribute substantially to the anti-inflammatory and hyperaemia-inducing effect. In animal studies and in vitro, faradiol demonstrated anti-inflammatory activity comparable to indomethacin.
- Gerbstoffe (Tannine): Procyanidine, hydrolysierbare GallotannineTanninContent: 0.5-1.5 %Flower
Mildly astringent tannins support decongestant and tissue-stabilising effects in external application. Complement the anti-inflammatory activity of sesquiterpene lactones and triterpenes.
- [1]MonographEMA/HMPC/198793/2012 — European Union herbal monograph on Arnica montana L., flos (Final, traditional use)(accessed: 2026-05-21)
- [2]MonographKommission E — Arnicae flos (Arnikablüten), Monographie (positiv), Bundesanzeiger Nr. 228, 1984 / revidiert 1990(accessed: 2026-05-21)
- [3]MonographESCOP Monographs — Arnicae flos (Arnica Flower), 2nd edition, supplement 2009(accessed: 2026-05-21)
- [6]MonographKnuesel O, Weber M, Suter A. Arnica montana gel in osteoarthritis of the knee: an open, multicenter clinical trial. Adv Ther. 2002;19(5):209-218. DOI:10.1007/BF02850361(accessed: 2026-05-21)
- [9]MonographCliniTox Giftpflanzen — Arnica montana L.: schwach giftig (+) (Institut für Veterinärpharmakologie und -toxikologie, Universität Zürich)(accessed: 2026-08-10)
- [4]BookWichtl, Max (Hrsg.) — Teedrogen und Phytopharmaka: Ein Handbuch für die Praxis, 5. Auflage, Wissenschaftliche Verlagsgesellschaft Stuttgart, 2009. Arnicae flos (S. 65–69).(accessed: 2026-05-21)
- [5]BookHänsel, Rudolf; Sticher, Otto — Pharmakognosie – Phytopharmazie, 9. Auflage, Springer Verlag, 2010. Kapitel: Sesquiterpenlactone; Arnica montana.(accessed: 2026-05-21)
- [7]BookKünzle, Johannes — Chrut und Uchrut: Praktisches Heilkräuterbüchlein, 1911 (Public Domain). Abschnitt Arnika.(accessed: 2026-05-21)
- [8]WikipediaEchte Arnika (Wikipedia DE)(accessed: 2026-05-21)
Classical quotes
"Arnica is a true wonder plant for contusions and sprains — but only when applied externally."